The Body Covers: The 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy Coverage
The 2nd International Workshop on Adverse Drug Reactions and Lipodystrophy
September 15, 2000
Andrew Carr then looked at a cohort of 221 HIV-infected men (32 naive, 42 of them on nucleoside analog-containing regimens and 147 on NNRTI-PI therapy) and found that approximately 3% of the patients have severe osteoporosis and that 22% had osteopenia. They found that patients with higher lactate levels were more likely to have osteopenia, as well as the patients with lower weight before starting therapy, which would be a marker of lower BMD at the time of starting therapy.
Dr. Glesby presented a case control study of avascular necrosis of the hip in HIV infected patients, a well known complication of HIV infection, whose prevalence is rising as shown recently in an NIH study presented at IDSA this year by Henry Masur group. Avascular necrosis of the hip was associated with prior PCP (probably a marker of previous corticosteroid use). Clinicians should be very aware of this complication because delays in the diagnosis and treatment are very frequent.
This article was provided by The Body PRO. Copyright © Body Health Resources Corporation. All rights reserved.