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The Body Covers: The 3rd International Conference on Nutrition and HIV Infection
Opening Session: The Changing Face of Malnutrition and HIV

April 22-25, 1999

A note from TheBody.com: Since this article was written, the HIV pandemic has changed, as has our understanding of HIV/AIDS and its treatment. As a result, parts of this article may be outdated. Please keep this in mind, and be sure to visit other parts of our site for more recent information!

The opening session was devoted to an update on HAART and an update on the changing face of malnutrition in HIV infection. Dr. Donald Kotler of New York presented the latter. Dr. Kotler stressed how far this field has come in 15 years. In 1984 we were just learning the extent of AIDS wasting and the role of body composition studies in its analysis. Now we have a much-improved understanding of this process even as the process itself has changed: less severe wasting with availability of both preventive and therapeutic interventions. Since 1997 awareness has developed of a syndrome of fat redistribution (FRS) associated with the development of unsightly and possibly unhealthy fat deposits, fat wasting in other locations, high levels of blood lipids and even diabetes. Dr. Kotler does not believe that these complications are directly related to protease inhibitor therapy as all have been reported in patients on non-PI containing regimens and even in some without any antiretroviral therapy. Indeed fat redistribution syndrome may actually correlate with an improved prognosis, namely longer survival. Dr. Kotler does not believe that the hypothesis of Carr and Cooper (from Australia) is correct, that the protease inhibitors directly affect a cellular enzyme involved in lipid metabolism. At this point explaining the mechanism behind fat redistribution syndrome is not possible.

A note from TheBody.com: Since this article was written, the HIV pandemic has changed, as has our understanding of HIV/AIDS and its treatment. As a result, parts of this article may be outdated. Please keep this in mind, and be sure to visit other parts of our site for more recent information!

See Also
An HIVer's Guide to Metabolic Complications
More Research on HIV/AIDS Wasting
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Please note: Knowledge about HIV changes rapidly. Note the date of this summary's publication, and before treating patients or employing any therapies described in these materials, verify all information independently. If you are a patient, please consult a doctor or other medical professional before acting on any of the information presented in this summary. For a complete listing of our most recent conference coverage, click here.

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