The 7th Conference on Retroviruses and Opportunistic Infections

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The 7th Conference on Retroviruses and Opportunistic Infections

San Francisco Marriott, San Francisco, California

January 30 - February 2, 2000

Conference Summaries
Reports and Related Articles


Mark Holodniy, M.D.	Ian Frank, M.D.	Rick Stryker, M.D., M.P.H.	Alvan Fisher, M.D.

The 7th Conference on Retroviruses and Opportunistic Infections draws 3,200 clinicians and basic scientists from around the world to present the latest research on HIV, AIDS, and opportunistic infections. The meeting is sponsored by the Foundation for Retrovirology and Human Health and is in scientific collaboration with the National Institute of Allergy and Infectious Diseases (NIAID) and the Centers for Disease Control and Prevention (CDC).

The Retrovirus Conference, regarded as one of the most important scientific gatherings of the year, was created to provide a forum for scientists and clinicians to present, discuss, and critique developments in the field of human retrovirology and related opportunistic complications. The subjects that will be highlighted are: virology, pathogenesis, host-virus interactions, pathology, immunology, epidemiology, diagnostics, prevention, therapy, pharmacology, and vaccines. In addition, new scientific studies concerning the diagnosis, treatment, and prevention of associated opportunistic infections will be included.

Reporting exclusively for The Body are Alvan Fisher, M.D., Rhode Island Hospital and Associate Professor, Brown University School of Medicine; Ian Frank, M.D., Hospital of the University of Pennsylvania and Associate Professor, University of Pennsylvania; Mark Holodniy, M.D., Veterans Affairs Medical Center and Associate Professor, Stanford University; Paul E. Sax, M.D., Brigham and Women's Hospital (BWH) in Boston and Associate Professor, Harvard Medical School; and Rick Stryker, M.D., Pacific Oaks Medical Group, Los Angeles, CA; Melanie A. Thompson, M.D., AIDS Research Consortium of Atlanta; Doug Ward, M.D., Dupont Circle Physicians Group, Washington, D.C.

In addition, the Seattle Treatment Education Project (STEP), publisher of the treatment journal, STEP Perspective, will be providing additional conference summaries. STEP reporters include: Dan Dawson, Editor of the STEP Perspective.

Funding for this conference coverage at The Body is provided, in part, by unrestricted educational grants from Agouron Pharmaceuticals, Bristol-Myers Squibb, DuPont Pharmaceuticals Company, Glaxo Wellcome, and Roxane Laboratories.

The Body's Conference Summaries
Day One Sunday, January 30	Day Two Monday, January 31	Day Three Tuesday, February 1	Day Four Wednesday, February 2
Opening Session Metabolic Abnormalities/Fat Redistribution: Prevalence, Incidence, and Risk Factors Gender Differences in Body Habitus Changes/Fat Redistribution Cardiovascular Complications of Antiretroviral Therapy Pathogenesis and Mechanisms of Metabolic Abnormalities Metabolic Complications: Effects of Switching Antiretroviral Therapy and Other Interventions Complications of Therapy: Mitochondrial Dysfunction/Lactic Acidosis Adherence to Chemotherapeutic Regimens Pharmacology: Drug Interactions Pharmacology of Antiretroviral Drugs New Drug Targets: Integrase Inhibitors Emerging Issues in Hepatitis C Infection Metabolic Complications of Antiretroviral Therapy	Management of the HIV-Infected Pregnant Woman HIV Entry and Its Inhibition Primary Infection Antiviral Therapy: Resistance and Reservoirs Primary and Secondary Prevention of Opportunistic Infections in the Era of HAART Pathogenesis and Treatment of Mycobacterial Infections Pathogenesis and Treatment of CMV Disease in the Era of HAART HIV-1 Dementia, PML, and Neurologic Complications of Therapy Metabolic Complications of Antiviral Therapy Immune Reconstitution in Pediatric HIV-1 Infection Immunotherapy and Treatment Interruption	Timing the Origin of the HIV Pandemic Antiviral Therapy: Clinical Trials Trends in HIV-Associated Mortality Novel Antiretroviral Agents: Protease Inhibitors Antiretroviral Therapy in Treatment-Naïve Patients Antiretroviral Chemotherapy: Treatment-Experienced Patients Immune-Based and Genetic Therapies Treatment of Primary Infection	Critical Issues in Antiretroviral Therapy Pediatric/Maternal-Fetal Treatment Issues Antiviral Therapy: New Drugs Issues in HIV-1 Infection in Women Maternal/Fetal and Pediatric Pharmacokinetics of Antiretroviral Therapy Resistance to Antiretroviral Drugs Genotypic and Phenotypic Characterization of HIV for Therapeutic Decision-Making Documentation of HIV-1 Superinfection and Acceleration of Disease Progression It Is Safe to Discontinue Secondary Prophylaxis for PCP in HIV-Infected Patients Treated with HAART Pharmacokinetic Interactions between Protease Inhibitors and Selected HMG-CoA Reductase Inhibitors A Randomized, Placebo-Controlled Trial of Saquinavir, Indinavir or Nelfinavir in Combination with Amprenavir, Abacavir, Efavirenz & Adefovir in Patients with PI Failure Virologic and Immunologic Evaluation of Structured Treatment Interruptions in Patients Experiencing Long-term Virologic Failure Structured Cyclic Antiretroviral Therapy Interruption in Chronic Infection May Induce Immune Responses Against HIV-1 Antigens Associated with Spontaneous Drop in Viral Load

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