ACRIA Studies in Progress

• Pregabalin for Peripheral Neuropathy
• TH9507 for Lipodystrophy
• UK-427,857 for Drug-Resistant HIV
• Research on Older Adults With HIV: ROAH Program

Pregabalin for Peripheral Neuropathy

People with HIV who have peripheral neuropathy will take either pregabalin (Lyrica) or a placebo (dummy pill) for 3 months. Participants must be 18 or older and have had pain in their hands or feet for at least 3 months.

TH9507 for Lipodystrophy

People who have excess abdominal fat and who are taking anti-HIV drugs will take either TH9507 (an experimental growth hormone releasing factor) or a placebo (dummy pill) for 26 weeks. Participants must be 18-65 years old, with a CD4 count over 100 and a viral load below 1,000.

UK-427,857 for Drug-Resistant HIV

People who have taken anti-HIV drugs from three of the four classes of drugs will either take UK-427 (an experimental HIV CCR5 attachment inhibitor) with an optimized regimen of anti-HIV drugs, or take a placebo (dummy pill) with an optimized regimen, for 11 months. Participants must be 16 or older and have a viral load of at least 5,000.

For the above trials, contact Dr. Douglas Mendez at 212-924-3934 ext. 126 or Dr. Yuriy Akulov at ext. 124.

Research on Older Adults With HIV: ROAH Program

People in this large study of older adults with HIV will fill out a survey about physical and behavioral health, social networks, quality of life and spirituality. Participants must be 50 or older and be able to read and complete a questionnaire. Study participants will be reimbursed $25 for one visit. Since the study is nearly completed, the only slots now available are for white men.

For the ROAH Program, contact Andrew Shippy at 212-924-3934 ext. 104.