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ACRIA Studies in Progress

Winter 2005/2006


Pregabalin for Peripheral Neuropathy

People with HIV who have peripheral neuropathy will take either pregabalin (Lyrica) or a placebo (dummy pill) for 3 months. Participants must be 18 or older and have had pain in their hands or feet for at least 3 months.


TH9507 for Lipodystrophy

People who have excess abdominal fat and who are taking anti-HIV drugs will take either TH9507 (an experimental growth hormone releasing factor) or a placebo (dummy pill) for 26 weeks. Participants must be 18-65 years old, with a CD4 count over 100 and a viral load below 1,000.


TMC 114 for Treatment-Experienced Adults

People who have taken anti-HIV drugs from three of the four classes of drugs (an NRTI, NNRTI and two PIs), and who have limited or no treatment options due to resistance or intolerance, will take TMC 114 (a new PI) along with other anti-HIV drugs. Participants must be 18 or older, have a CD4 count below 200 and must not be eligible for any other Tibotec-sponsored HIV trial.

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Maravicoc (UK-427,857) for Drug-Resistant HIV

People who have taken anti-HIV drugs from three of the four classes of drugs will either take maraviroc (an experimental HIV CCR5 attachment inhibitor) with an optimized regimen of anti-HIV drugs, or take a placebo (dummy pill) with an optimized regimen, for 11 months. Participants must be 16 or older and have a viral load of at least 5,000.

For the above trials, contact Dr. Douglas Mendez at 212-924-3934 ext. 126 or Dr. Yuriy Akulov at ext. 124.





  
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This article was provided by AIDS Community Research Initiative of America. It is a part of the publication ACRIA Update. Visit ACRIA's website to find out more about their activities, publications and services.
 

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