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Resistance Rules - Revised

August/September 1996

Resistance Rules - Revised

Amino acid substitutions conferring reduced sensitivity to selected protease inhibitors:

saquinavir (Invirase)10 485463
ritonavir (Norvir)2036 465463 718284 90
indinavir (Crixivan)102024364654636471828490193
nelfinavir (Viracept)30364663778890
141W94 (aka VX478)1046475084

Amino acid substitutions in HIV isolates from patients; predominant in vivo substitutions are underscored.

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