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Pediatric Information -- Table II

From U.S. Food and Drug Administration

Updated December 18, 1997

  Norvir™ Abbott
ritonavir 		Viracept® Agouron
nelfinavir
Pediatric Dosage 400 mg/m< bid not to exceed 600 mg bid 20-30 mg/kg tid not to exceed 750 mg tid
Pediatric Dosage
Initiations/Adjustments 		Ritonavir should be started at 250 mg/m<and increased every 2-3 days by 50 mg/m< twice daily.

If 400 mg/m< is not tolerated, the highest tolerated dose should be used for maintenance therapy in combination with nucleoside analogues.

 --------
Pediatric Dosage
Guidelines		 See Table A See Table B
Pediatric Age Range
Studied		 2-14 years pharmacokinetic study 2-13 years pharmacokinetic study
Pediatric Mixing
Recommendations		 Oral solution does not require mixing. Dose should be administered using a calibrated dosing syringe. Oral Powder may be mixed with a small amount of water, milk, formula, soy formula, soy milk or dietary supplements. Oral powder should not be reconstituted with water in its original container. Acidic food or juice (e.g.orange juice, apple juice or apple sauce) are not recommended to be used with the Oral Powder because it may result in bitter taste.

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This article was provided by U.S. Food and Drug Administration. It is a part of the publication Protease Inhibitors Backgrounder.
 
 

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