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October 1997

EDITORIAL

A Kiss Is Just a Kiss

How to allay your patients' concerns about that C.D.C. case of purported oral-oral transmission
PAUL A. VOLBERDING, M.D.



OPTIMAL MEDICAL MANAGEMENT

The Challenge of Multidrug-Resistant Tuberculosis

The clinical features, diagnosis, and treatment of TB in patients with HIV infection
ROBERT M. JASMER, M.D., and LAURENCE HUANG, M.D.



NEWSLINE

Newsline...Newsline...Newsline...

Predictors of TB infection: Geographical region and induration size of positive PPD test help identify those at risk... Isoniazid in HIV-positive patients at high risk for TB: Six months of prophylaxis produces no benefit... C.D.C. data can help clinicians identify patients at high risk for drug-resistant TB... Combivir®, first two-in-one antiretroviral agent, wins F.D.A. approval..."Prevention Works!," an update: Skills-building prevention programs for men who have sex with men prove effective -- and cost-effective as well... Broad-based prevention programs have little impact on high-risk behavior, but targeted interventions produce results... Transmission risk can be reduced among IDUs, but only when indirect risks are also addressed...

Plus: Guidelines for the Administration of Protease Inhibitors and Rifampin in HIV-Positive Patients with Tuberculosis



PULL OUT AND SAVE

Foods That Can Be Eaten in Conjunction with Crixivan

A list of low-fat and no-fat snacks that your patients can take along with their indinavir dose, if they need to eat at a scheduled dosing time



CASE MANAGEMENT

Joan J., a Treatment-Naïve Patient Who Isn't Naïve About Treatment Options

Is this individual a candidate for aggressive suppression therapy?
HARVEY J. MAKADON, M.D.




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