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Table of ContentsOctober 1998
IN MEMORIAM
We Will Prevail Together
The enduring legacy of Jonathan M. Mann and Mary Lou Clements-Mann
OPTIMAL MEDICAL MANAGEMENT Prophylaxis of OIs in the Age of Protease Inhibitors -- An Update
New information -- and accumulating clinical experience -- suggest that it may be possible to withdraw some types of prophylaxis without putting patients at risk of developing opportunistic infections
NEWSLINE Newsline ... Newsline ... Newsline ...Simultaneous initiation of three-drug regimen more effective than adding drugs sequentially: More evidence favoring an aggressive approach to therapy ... Five-drug regimen produces sharp reductions in viral load: Experimental combination may be useful in patients with high baseline HIV RNA levels ... Genotype and disease progression: A clearer picture of the role that CCR5 plays in HIV infection ... Reservoirs of HIV infection: Replication-competent virus found in tonsillar tissue ... Interleukin-2: Unfortunately, subcutaneous injections are not as effective as continuous infusion ... Infectious HIV found in genital herpes lesions: Reactivation of HSV leads to increased viral load on mucosal surfaces ... CASE MANAGEMENT John D., a Patient Who Has Failed All Conventional Therapies
What options do patients -- and providers -- have when salvage therapy is indicated?
This article was provided by San Francisco General Hospital. It is a part of the publication HIV Newsline.
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