Objective: To review behavioral decision theory and research to identify implications for informed consent.
Research Design: Traditional literature review and hand search of literature were used.
Results: Psychological research on biases and heuristics identifies cognitive biases in information processing (selection and interpretation of risks and benefits) that have implications for improving the informing process. A growing literature on patient decision aids provides evidence for the feasibility of more fully informing patients, and includes examples of "de-biasing" procedures (to improve information comprehension and consent).
Conclusions: Informing and consenting involve conceptually different challenges concerning effectiveness versus values. De-biasing techniques need to be developed and empirically tested to determine their effectiveness in informing patients. Consenting involves both social and individual values. Appealing to altruism when summarizing the goals of research may increase research participation and does not necessarily violate voluntariness of informed consent. [M. Holmes-Rovner and C.E. Wills; Med Care; 2002 Sep;40(9 Suppl):V-V308.]
Back to the October 2002 issue of IAPAC Monthly.