Print this page    •   Back to Web version of article

Prevention/Epidemiology
NIAID Awards $16.8 Million Grant to AlphaVax for HIV Vaccine Development

October 22, 2003

Research Triangle Park, N.C.-based biotechnology company AlphaVax on Monday announced that it will receive an additional $16.8 million in National Institute of Allergy and Infectious Diseases grant funds to advance the development of the firm's experimental HIV vaccine, the Raleigh News & Observer reports (Ranii, Raleigh News & Observer, 10/21). Last month, NIAID awarded $81 million in five-year grants to four biotech companies -- including AlphaVax -- as part of NIAID's HIV Vaccine Design and Development Teams program, which is a public-private partnership aimed at accelerating HIV vaccine development. AlphaVax's vaccine uses a nonreplicating alphavirus to deliver the genes to make four HIV proteins. The genes are from HIV strains present in Southern Africa. In animal models, the vaccine induced strong cellular and antibody immune system responses (Kaiser Daily HIV/AIDS Report, 9/30). The new grant will be used to add more genes to the vaccine, which could cause a more "potent" immune response, the News & Observer reports. AlphaVax in July started clinical trials involving 48 healthy participants to test the safety and immune potential of its HIV vaccine (Raleigh News & Observer, 10/21). Michael Pensiero, who oversees NIAID's HIV/AIDS contracts and grants, said that AlphaVax received the grants in part because their vaccine technology is "novel, as well as promising," according to the News & Observer. He added that the agency "wants to see a variety of different approaches" for an HIV vaccine (Raleigh News & Observer, 10/21).

Back to other news for October 22, 2003


Reprinted with permission from kaisernetwork.org. You can view the entire Kaiser Daily HIV/AIDS Report, search the archives, or sign up for email delivery at www.kaisernetwork.org/dailyreports/hiv. The Kaiser Daily HIV/AIDS Report is published for kaisernetwork.org, a free service of the Kaiser Family Foundation, by The Advisory Board Company. © 2003 by The Advisory Board Company and Kaiser Family Foundation. All rights reserved.




This article was provided by Henry J. Kaiser Family Foundation. It is a part of the publication Kaiser Daily HIV/AIDS Report. You can find this article online by typing this address into your Web browser:
http://www.thebody.com/content/art11517.html

General Disclaimer: TheBody.com is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through TheBody.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.