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As HIV Community Ages, Study Seeks to Address Inflammation

April 29, 2015

As the HIV community continues to thrive and get older, part of the focus shifts to ensuring that this population continues to do well by preventing inflammation and comorbidities. In 2011, people over age 55 accounted for 26% of the estimated 1.2 million people living with HIV in the U.S., according to the U.S. Centers for Disease Control and Prevention (CDC).

The AIDS Clinical Trial Group (ACTG) provided an update of its current study, "A5322 -- Long-term Follow-up of Older HIV-infected Adults: Addressing Aging, HIV Infection & Inflammation (HAILO)," in this month's ACTG newsletter.

According to the update:

The A5322 clinical team successfully enrolled approximately 1,000 HIV-positive participants aged 40 or older. These individuals are diverse in their cART [combination antiretroviral therapy] treatment experience, their co-morbid illnesses and their overall states of health. One extremely encouraging finding of this study has been how well-controlled HIV infection has remained for the vast majority of participants -- many of whom initiated cART more than 10-12 years ago. There is also an incredible amount of diversity in terms of co-morbid illnesses that are being treated simultaneously in these participants. It is important that illnesses (and their treatments) that are common among aging persons, such as hypertension, diabetes mellitus, and hyperlipidemia, are well-represented in this study.

The study is ongoing and will follow participants for seven years, and hopes to discover more on the relationships between HIV infection, age, the immune system and development of comorbidities.

Warren Tong is the senior science editor for and

Follow Warren on Twitter: @WarrenAtTheBody.

Copyright © 2015 Remedy Health Media, LLC. All rights reserved.

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