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CROI 2014: How Depression Impacts HIV (Video)

By Barbara Jungwirth

April 14, 2014

Esteban Martínez, M.D., Ph.D., and Karl Goodkin, M.D., sit down to talk about the connection between depression, control of HIV and heart failure. Overall, HIV-infected patients have a 45% lifetime risk of a depressive disorder, compared to a 4%-7% risk in the general population. This may be partly due to HIV's effect on the central nervous system, according to one study presented at CROI 2014.

The panelists also discuss studies that showed a link between depression and myocardial infarction, as well as a decline in depression as viral load is better suppressed. While viral load may be driving depression, this mental health issue is also driving viral load through a lack of adherence or retention in care. Additionally, they explain that depression is underdiagnosed in the U.S. and Spain, and hypothesize that this may contribute to the difficulty of controlling HIV in certain individuals.

Watch the video to learn more:

More on the panelists:

The video above has been posted on with permission from our partners at the International Foundation for Alternative Research in AIDS (IFARA). Visit IFARA's website or YouTube channel to watch more video interviews from the conference, as well as earlier meetings.

Barbara Jungwirth is a freelance writer and translator based in New York.

Follow Barbara on Twitter: @reliabletran.

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