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Medical News

Researcher Develops New Medicine That Attacks HIV Before It Integrates With Human DNA

October 30, 2013

This article was reported by Medical Xpress.

An article reported in Medical Xpress discusses a new drug that attacks HIV before it integrates with human DNA. According to Vasu Nair, the Georgia Research Alliance's eminent scholar and director of the University of Georgia (UGA) Center for Drug Discovery at UGA College of Pharmacy, this HIV integrase inhibitor is very effective against many types of HIV.

Nair explained that in the beginning stage of HIV infection, the immune system releases antibodies to defend the body from the invading virus. Helper T-cells called CD4+ cells are important in the body's immune response and organize the other cells in the immune system to do their work. HIV attaches itself to the outer surface of the CD4+ cell, enters it, releases 15 viral proteins and ribonucleic acid, and uses the human cellular biochemistry to reproduce in large numbers. The virus uses HIV integrase, a viral enzyme, to help it enter human DNA, reproduce, and destroy

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