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Targeting the Macrophage Reservoir: Early Steps Toward an HIV Cure (Video)

By Warren Tong

September 11, 2013

"Can we define where the virus is hiding during ART and then can we eliminate that?" That's the question that Jonah Sacha, Ph.D., of Oregon Health and Science University is asking.

In this interview, Sacha sits down with Fred Schaich, of the International Foundation for Alternative Research in AIDS (IFARA), to talk about his work looking for an HIV cure, which is currently in its early stages.

"We are examining the reservoir that's present in macrophages, which is one of the major targets of the virus. Most people focus on CD4 T cells because they're the major target of the virus, but macrophages are also important," Sacha explains, adding that macrophages are located in every tissue of the body and critical for every biological function. Sacha also touches upon the work he's doing using CMV (cytomegalovirus) as an HIV vaccine vector.

The video above has been posted on with permission from our partners at the International Foundation for Alternative Research in AIDS (IFARA). Visit IFARA's website or YouTube channel to watch more video interviews from the conference, as well as earlier meetings.

Warren Tong is the research editor for and

Follow Warren on Twitter: @WarrenAtTheBody.

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