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Medical News

A New Drug Shows Promise of Hepatitis C Cure

March 29, 2013

Researchers report success in blocking the hepatitis C virus's ability to colonize liver cells in 18 hepatitis C-infected patients with five weeks of treatment using the antisense oligonucleotide miravirsen. Fourteen weeks after miravirsen injections ended, hepatitis C viral loads were still undetectable in 5 of 18 patients.

Miravirsen binds tightly to messenger proteins of liver cells and blocks the hepatitis C virus from colonizing the proteins, which the virus needs to survive and replicate. Without a foothold in liver cells, the hepatitis C virus does not have the chance to develop resistance to protease inhibitors such as teleprevir and boceprivir. As a result, hepatitis C patients could be able to stop taking interferon and ribavirin, which cause side effects like

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See Also
Talk to a Physician About HIV/Hepatitis Coinfection in Our "Ask the Experts" Forums
More on Hepatitis C Drugs in Development

Reader Comments:

Comment by: john q. public (not important) Sat., Mar. 30, 2013 at 12:18 pm EDT
So, with this drug, you get fatty liver,liver fibrosis, and liver tumors. Go back to the drawing board. These side effects are just what the patient is trying to avoid. What's wrong with your science?

And you want to inject this into people? No thanks.
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