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More on HIV and Aging: One Study Whose Impact Will Last Well Beyond CROI 2013

By Josep M. Llibre, M.D., and Benjamin Young, M.D., Ph.D.

March 14, 2013

It's expected that half of the U.S. HIV-infected population will be over the age of 50 soon. For this reason, there has been growing interest in the spectrum of non-AIDS medical complications in HIV-infected people. Key questions focus on whether the rates of these complications are higher, or occur at a younger age, in HIV-infected persons.

Data from the massive and well-characterized Veterans Aging Cohort Study (VACS), comparing 68,558 HIV-uninfected to 31,454 HIV-infected people, were presented. HIV-infected individuals had greater rates of myocardial infarction, end-stage renal disease and HIV-associated cancer. However, there were no differences in the rate of other cancers, nor were there differences in the mean age at heart, kidney or non-AIDS cancer diagnosis.

These data argue against the development of myocardial infarction, end-stage renal disease or non-AIDS cancers at younger ages in HIV-infected individuals.

Which other studies presented at CROI 2013 will have lasting impact long after memories of the conference itself have faded? Read more of Dr. Llibre and Dr. Young's top picks.

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