HIV Vaccine Primer: Basic Science and Concepts
May 13, 2013
A DNA vaccine is a vaccine that uses the genetic code of a pathogen inserted into a circular piece of DNA called a plasmid to invoke an immune response. With a DNA vaccine, trial participants cannot become infected because only those genes that code for the pathogen's antigens are used, never the whole pathogen. The genes are taken up by some cells in the body, which then produce the antigens that train the immune system to recognize the targeted pathogen. This approach has shown promising results, and trials are ongoing.
Perhaps the most common vaccine approach used in HIV research is a recombinant vector vaccineView Full Article
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