An Overview of Dolutegravir
August 23, 2013
Brand Name: Tivicay
Dolutegravir can cause serious, life-threatening side effects. These include allergic reactions.
Contact your health care provider right away if you have a rash.
Stop taking dolutegravir and contact your health care provider right away if you have any of the following symptoms that may signal liver problems:
Do not take dolutegravir if you take dofetilide. Taking dolutegravir and dofetilide can cause side effects that may be life threatening.
What Is Dolutegravir?
Dolutegravir is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 12 years of age and older and weighing at least 88 pounds (40 kilograms). Dolutegravir is always used in combination with other anti-HIV medicines.
Dolutegravir is a type of anti-HIV medicine called an integrase inhibitor. Dolutegravir works by blocking integrase, an HIV enzyme. This prevents HIV from replicating and lowers the amount of HIV in the blood.
Dolutegravir does not cure HIV/AIDS. It is not known if dolutegravir reduces the risk of passing HIV to other people.
What Should I Tell My Health Care Provider Before Taking Dolutegravir?
Before taking dolutegravir, tell your health care provider:
How Should I Take Dolutegravir?
Dolutegravir comes in tablet form. Each tablet contains 50 mg dolutegravir (brand name: Tivicay).
Take dolutegravir according to your health care provider's instructions.
Take dolutegravir by mouth, with or without food. Do not change your dose or stop taking dolutegravir without talking with your health care provider first.
Always take dolutegravir in combination with other anti-HIV medicines.
If you take too much dolutegravir, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.
For more information on how to take dolutegravir, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
What Should I Do If I Forget a Dose?
Take the missed dose as soon as you remember it. But if it is within 4 hours of your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.
What Side Effects Can Dolutegravir Cause?
Dolutegravir can cause serious, life-threatening side effects. These include allergic reactions. (See the WARNING above.)
Other possible side effects of dolutegravir include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of dolutegravir. Ask your health care provider or pharmacist for more information on side effects of dolutegravir.
How Should Dolutegravir Be Stored?
Where Can I Find More Information About Dolutegravir?
More information about dolutegravir is available:
The above Patient Version drug summary is based on the following FDA label(s): Tablet (film coated).
This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
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