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Medical News

Vertex Ends Work on One Hepatitis Drug, Continues Another

September 26, 2012

Vertex Pharmaceuticals announced the discontinuation of work on the experimental hepatitis C drug ALS-2158 and resumption of development on another hepatitis C drug, ALS-2200. ALS-2158, which was being developed with partner Alios BioPharma Inc., did not show enough efficacy. On the other hand, ALS2200 showed promise in an early trial. The company is planning a mid-stage or Phase II trial of ALS-2200 in combination with ribavirin and one trial to evaluate ALS-220 in combination with the existing drug Incivek. Incivek, which must be taken with interferon, was approved in 2011 and so far has doubled the cure rate of prior standard treatments.

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