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An Overview of Stribild (Elvitegravir/Cobicistat/FTC/Tenofovir)

November 30, 2012

Brand Name: Stribild
Other Names: QUAD, elvitegravir/GS-9350/emtricitabine/tenofovir disoproxil fumarate
Drug Class: Combination Drugs
Approved Use: Treatment of HIV Infection

WARNING:

Stribild can cause serious, life-threatening side effects. These include lactic acidosis (buildup of acid in the blood) and liver problems.

Contact your health care provider right away if you have any of the following symptoms that may signal lactic acidosis:

Contact your health care provider right away if you have any of the following symptoms that may signal liver problems:

Stribild is not approved for the treatment of hepatitis B virus (HBV) infection. People co-infected with HIV and HBV who stopped taking emtricitabine or tenofovir disoproxil fumarate, which are two anti-HIV medicines included in Stribild, have had severe worsening of their HBV infections. The HBV drug adefovir dipivoxil (brand name: Hepsera) should not be taken with Stribild.

While taking Stribild, it is important to keep all of your appointments with your health care provider.


What is Stribild?

Stribild is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults who have never taken HIV medicines before. Stribild is a complete regimen for the treatment of HIV infection and should not be used in combination with other anti-HIV medicines.

Stribild contains the following four medicines combined in one pill: elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate. Elvitegravir is a type of anti-HIV medicine called an integrase inhibitor. Cobicistat is a type of medicine called a pharmacokinetic enhancer. It is used to increase the effectiveness of elvitegravir. Emtricitabine and tenofovir disoproxil fumarate are types of anti-HIV medicines called nucleoside reverse transcriptase inhibitors (NRTIs). The four drugs in combination prevent HIV from replicating and lower the amount of HIV in the blood.

Stribild does not cure HIV/AIDS. It is not known if Stribild reduces the risk of passing HIV to other people.


What should I tell my health care provider before taking Stribild?

Before taking Stribild, tell your health care provider:


How should I take Stribild?

Stribild comes in tablet form. Each tablet contains:

Take Stribild with food. Do not take Stribild in combination with other anti-HIV medicines.

If you take too much Stribild, contact your local poison control center (1-800-222-1222) or go to the nearest hospital emergency room right away.

For more information on how to take Stribild, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)


What should I do if I forget a dose?

Take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take two doses at the same time to make up for a missed dose.


What side effects can Stribild cause?

Stribild can cause serious, life-threatening side effects. These include lactic acidosis (buildup of acid in the blood) and liver problems. (See the WARNING above).

Other possible side effects of Stribild include:

Tell your health care provider if you have any side effect that bothers you or that does not go away.

These are not all the possible side effects of Stribild. Ask your health care provider or pharmacist for more information on side effects of Stribild.


How should Stribild be stored?


Where can I find more information about Stribild?


Manufacturer Information

Gilead Sciences
800-445-3235




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