HIV infects cells of the immune system and reprograms them to spew out copies of the virus. But not all of these HIV-infected cells roam freely in the body; some HIV goes into hibernation instead, avoiding the attention of the immune system and of antiretrovirals. This hibernation is called "latent infection." It results in "reservoirs" of undetected HIV tucked away in various parts of the body, ready to seed the body with more of the virus when triggered.
There is still much we don't know about how latent HIV infection works, but many experts believe that if a way can be found to find this hidden HIV and eliminate its reservoirs in the body, it may bring us one huge step closer to a cure.View Full Article
Comment by: Ricardo
Wed., Apr. 11, 2012 at 12:31 pm UTC
ARVs will never be able to kill the virus. They were not designed for that.
is not the same: (sentences one and two)
1. stop the cycle of a virus inside the cell. If a drug does this. it is expected that if one stops the drug ... the virus will continue its cycle. I do not think this virus is hiding.
2. remove the virus to a cell.
The concept of the reservoir would be logical if:
If after a procedure to remove the virus from the body .... the virus appeared out of nowhere, then one might think that there is a place where this virus is hiding. ie the so-called sanctuaries.
but there is no medicine to remove viruses from infected cells.
the experimental procedure that Dr. Margolis is working is contradictory.
Have a drug that stops the virus cycle and at the same time you add a drug that wakes up the cells infected with HIV virus.
The procedure of Dr. Margolis will take many years (20 years) to have some conclusion (many years to have a conclusion)
And there is no guarantee that its findings are an outcome beneficial to society
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