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March/April 2012

Brand name: Not yet established

Generic name: dolutegravir, or DTG

Class: Integrase inhibitor (integrase strand transfer inhibitor, or INSTI)

Manufacturer: ViiV Healthcare,, (877) 844-8872 and Shionogi,, (800) 844-8872

AWP: TBD; investigational drug at press time.

Standard Dose: One 50 mg tablet once a day chosen for Phase 3 research. Twice-daily dosing was shown to work better in people who have viral resistance to Isentress and the investigational elvitegravir in a short study, VIKING Cohort II, and a large ViiV Phase 3 trial will look at the twice-daily dose. Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose.

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Visit Positively Aware's website to find out more about the publication.
See Also
The 16th Annual HIV Drug Guide
More on HIV Medications
Other Integrase Inhibitors

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