HIV Trial Scrapped After Gel Found to Be Ineffective
November 29, 2011
A routine review of data from a large clinical trial found that a tenofovir-based vaginal gel was not effective in preventing HIV in women, researchers reported Friday.
In 2010, the CAPRISA (Center for the AIDS Program of Research in South Africa) study in South Africa found a tenofovir-based microbicide vaginal gel was 39 percent more effective than placebo gel when used before and after sex. In regular users, it was 54 percent effective. The VOICE study, begun in 2009 with 5,029 sexually active HIV-negative women in South Africa, Uganda, and Zimbabwe, was expected to back those findings. Instead, the interim data review found no difference between theView Full Article
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