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What's New in the U.S. DHHS Antiretroviral Therapy Guidelines for Adults and Adolescents

October 14, 2011

The following appears at the beginning of the Oct. 14, 2011, revision to the Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents.

This revision to the January 10, 2011, guidelines is focused on What to Start: Initial Combination Regimens for the Antiretroviral-Naive Patient. Additions and key changes to the section are outlined below. More detailed discussion of the rationale for changes to the What to Start recommendations can be found in the updated section. Tables in the guidelines corresponding to the What to Start section have also been updated to reflect changes.

Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI)-Based Regimens

Protease Inhibitor (PI)-Based Regimens
Raltegravir-Based Regimens
Dual-Nucleoside Reverse Transcriptase Inhibitor (NRTI) Options

In addition to the changes highlighted above, the following tables are updated with information relevant to rilpivirine:

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