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FDA Approves Complera (Edurant + Truvada), a Second "All-in-One" Option for First-Line HIV Treatment

August 10, 2011

When it comes to single-pill HIV treatment regimens in the U.S., Atripla is no longer the only game in town. The U.S. Food and Drug Administration has just approved Complera, a once-daily tablet that contains Truvada (tenofovir/FTC) and the NNRTI Edurant (rilpivirine).

The approval of Complera has been highly anticipated for months. The drugs within the pill are similar to Atripla, which contains Truvada and an older NNRTI, Sustiva (Stocrin, efavirenz). In fact, Complera has frequently been referred to informally as "Btripla" by researchers, health care professionals and advocates. In a head-to-head study, the drugs that comprise Complera generally did just as good a job at controlling

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See Also
Next Single-Pill HIV Treatment Approved, and It's Not Called "B-Tripla"
Approval of Complera: Emtricitabine/Rilpivirine/Tenofovir DF Fixed-Dose Combination (Official FDA Announcement)
Edurant (Rilpivirine): The HIV Treatment Dating Game Just Got More Interesting
More News & Research on Complera (Rilpivirine/Tenofovir/FTC)

Reader Comments:

Comment by: mario (saucedo) Thu., Dec. 29, 2011 at 12:29 am EST
i am the owner of solano Aids coalition a company that provide services to families affected and infected by the HIV virus,i am HIV positive my self i been taking atripla for the last 5 years and i have horrible side effects like nausea,knight mares, insomnia,etc.
that's nice to know that we have another choice of treatment.
thank you
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Comment by: africa (luanda) Fri., Aug. 12, 2011 at 5:56 am EDT
hi there,
im in Africa and ill be moving soon to LA i want to know if when i get there ill get help if i need to if the HIV clinic there will able to help me without alot of complication and gaving me the med. if i need it, ill be taking anough but you never know, and if i want to change the Med will be ok.
right now im taking Trimune if that wont couse alot of demage in me im one of the luck people that dosent have alergy in medication i never had any side affect so will that be ok?

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Comment by: Katende (Kampala, Uganda) Thu., Aug. 11, 2011 at 11:05 pm EDT
Thank you for that wonderful drug (complera) even is one of the best drugs in the promotion of good adherence here in Uganda but it's only in Hospitals supported by partners like MSF our government can not afford the price and our biggest challenge is adherence when it comes to many drugs and times of taking drugs. Drug resistance rate is increasing such drugs could be of much help. "Support Uganda friends"
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