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First-Line HIV Medications

Since the late 1980s, more than 30 medications and drug-combination pills have been approved by the U.S. Food and Drug Administration to treat HIV. However, not all of these meds are recommended for first-line HIV treatment.

Using the links in the list below, you can learn more about each of the drugs that are considered acceptable options as part of a first-line HIV treatment regimen, according to official U.S. treatment guidelines. (If you'd like to see a complete listing of all approved HIV medications, visit our main medications page.)


Atripla (Efavirenz/Tenofovir/FTC)
The Basics | News | Research

Combivir (AZT/3TC)
The Basics | News | Research

Complera (Rilpivirine/Tenofovir/FTC)
The Basics | News & Research

Edurant (Rilpivirine, TMC278)
The Basics | News | Research

Emtriva (Emtricitabine, FTC)
The Basics | News | Research

Epivir (3TC, Lamivudine)
The Basics | News | Research

Epzicom (Abacavir/3TC, Kivexa)

Invirase (Saquinavir)
The Basics | News | Research

Isentress (Raltegravir, MK-0518)
The Basics | Research

Kaletra (Lopinavir/Ritonavir)
The Basics | News | Research

Lexiva (Fosamprenavir, Telzir)
The Basics | Research

Norvir (Ritonavir)
The Basics | News | Research

Prezista (Darunavir)
The Basics | News | Research

Retrovir (Zidovudine, AZT)
The Basics | News | Research

Reyataz (Atazanavir)
The Basics | News | Research

Selzentry (Maraviroc, Celsentri)
The Basics | News | Research

Stribild (Elvitegravir/
Cobicistat/FTC/Tenofovir)
The Basics | News | Research

Sustiva (Efavirenz, Stocrin)
The Basics | News | Research

Tivicay (Dolutegravir)
The Basics | News | Research

Truvada (Tenofovir/FTC)
The Basics | News | Research

Videx (Didanosine, ddI)
The Basics | News | Research

Viramune (Nevirapine)
The Basics | News | Research

Viread (Tenofovir)
The Basics | News | Research

Ziagen (Abacavir)
The Basics | News | Research







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