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Treatment Guidelines

The U.S. has highly respected official guidelines on when the best time is for a person to start HIV meds, as well as what to start treatment with. They currently recommend:

First-Line Regimens

To learn more about each of the HIV meds that U.S. guidelines list as potential first-line drugs, browse this page or pick from the list below:


When to Start

  • CD4 count above 500: Starting is worth considering.
  • CD4 count between 350 and 500: Starting is recommended.
  • CD4 count below 350 (or if you've ever had an AIDS-defining illness): Start as soon as possible.

To learn more about the latest HIV/AIDS treatment guidelines, read this rundown or download the full (and very detailed) official document.





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