October 24, 2015
Table of Contents
Many women living with HIV (HIV+) experience menstrual changes (changes in their periods). It is important to discuss any changes with your health care provider.
The changes women living with HIV may experience include:
Studies have found that menstrual irregularities (changes to your menstrual cycle) are less common if you have a high CD4 cell count and are taking HIV drugs. Menstrual irregularities are more common if you have a low CD4 cell count or high viral load or are significantly below your ideal body weight.
We are not sure exactly how HIV affects women's menstrual cycles. However, we do know that, as HIV gets worse, changes in your immune system can affect the way your body makes and maintains levels of different hormones including testosterone, estrogen, and progesterone. Changes in the amount of estrogen or progesterone could result in a number of menstrual changes for women living with HIV.
Research has shown that women with more advanced HIV disease (CD4 counts below 200), were more likely to have irregular menstrual cycles. Some of the factors that are more likely to occur in women with advanced HIV (wasting and loss of body fat, anemia, nutritional problems) can also lead to menstrual changes because they affect the hormones that control your menstrual cycle. It is important to know that these same issues also affect the menstrual cycles of women who are HIV-negative. For example, women with very low body fat (e.g., elite athletes), women with chronic illnesses not related to HIV, and women with low iron (one cause of anemia), are more likely to have irregular periods or no periods at all.
Because there are many possible reasons for menstrual changes, it is very important to have regular check-ups with your women's health care provider (often known as a "gynecologist" or "GYN") and to discuss any changes to your menstrual cycle.
Women living with HIV are more likely to be infected with the human papilloma virus (HPV), which can cause cervical cancer. Therefore, it is recommended that women living with HIV get a test to look for cervical cancer regularly. For more information about gyn care and tests for HPV and cervical cancer, see The Well Project's article, Caring for a Woman's Body: What Every Woman Should Know about the Care and Prevention of GYN Problems.
If you miss two or more periods in a row, have heavy bleeding, or have bleeding between periods, see your women's health care provider for a pelvic examination, a test for cervical cancer, and blood tests. These blood tests may check your red blood cell and platelet counts as well as your estrogen and progesterone levels. They will likely test for pregnancy and common sexually transmitted infections (like Chlamydia) that can affect your reproductive system. Your health care provider may also use additional tests such as ultrasound (sonography) to check for causes of irregular periods.
Possible causes for irregular periods include:
Cervical cancer takes years to develop. Often women who have cervical cancer - and who have not had a Pap test, VIA test (Visual Inspection with Acetic Acid), or DNA test looking for cervical cancer - do not know they have it until it is quite advanced. This is why getting a test done regularly is so important.
When dealing with menstrual problems, your provider will likely:
Even though menstrual problems are common, suffering with them is not a normal part of HIV. In most cases, it is possible to find the cause of your symptoms and to treat or manage the problem. Try to keep track of the start/end dates of your periods each month. It is important to get regular gyn exams as part of your routine health care, and to report any changes in your menstrual cycle to your health care provider.