Menstrual Changes and HIV
July 23, 2014
Table of Contents
- HIV and Menstrual Problems
- How Does HIV Cause Problems?
- Finding the Cause of Menstrual Problems
- What Else Can Cause Menstrual Problems?
- Dealing With Menstrual Problems
- Taking Care of Yourself
Many women living with HIV (HIV+) experience menstrual changes (changes in their periods). It is important to discuss any changes with your health care provider.
The changes HIV+ women may experience include:
- Irregular periods:
- Different in frequency (how often)
- Different in duration (how long)
- Different in amount (lighter or heavier)
- Missed periods
- No period for more than 90 days (amenorrhea)
- Spotting (spots of blood between periods)
Studies have found that menstrual irregularities (changes to your menstrual cycle) are less common if you have a high CD4 cell count and are taking HIV drugs. Menstrual irregularities are more common if you have a low CD4 cell count or high viral load or are significantly below your ideal body weight.
We are not sure exactly how HIV affects women's menstrual cycles. However, we do know that, as HIV gets worse, changes in your immune system can affect the way your body makes and maintains levels of different hormones including testosterone, estrogen, and progesterone. Changes in the amount of estrogen or progesterone could result in a number of menstrual changes for HIV+ women.
Research has shown that women with more advanced HIV disease (CD4 counts below 200), were more likely to have irregular menstrual cycles. Some of the factors that are more likely to occur in women with advanced HIV (wasting and loss of body fat, anemia, nutritional problems) can also lead to menstrual changes because they affect the hormones that control your menstrual cycle. It is important to know that these same issues also affect the menstrual cycles of women who are HIV-negative. For example, women with very low body fat (e.g., elite athletes), women with chronic illnesses not related to HIV, and women with low iron (one cause of anemia), are more likely to have irregular periods or no periods at all.
Because there are many possible reasons for menstrual changes, it is very important to have regular check-ups with your women's health care provider (often known as a "gynecologist" or "GYN") and to discuss any changes to your menstrual cycle.
Women living with HIV are more likely to be infected with the human papilloma virus (HPV), which can cause cervical cancer. Therefore, it is recommended that HIV+ women get a test to look for cervical cancer regularly. For more information about gyn care and tests for HPV and cervical cancer, see The Well Project's article, Caring for a Woman's Body: What Every Woman Should Know about the Care and Prevention of GYN Problems.
Cervical cancer takes years to develop. Often women who have cervical cancer - and who have not had a Pap test, VIA test (Visual Inspection with Acetic Acid), or DNA test looking for cervical cancer - do not know they have it until it is quite advanced. This is why getting a test done regularly is so important.
If you miss two or more periods in a row, have heavy bleeding, or have bleeding between periods, see your women's health care provider for a pelvic examination, a test for cervical cancer, and blood tests. These blood tests may check your red blood cell and platelet counts as well as your estrogen and progesterone levels. They will likely test for pregnancy and common sexually transmitted infections (like Chlamydia) that can affect your reproductive system. Your health care provider may also use additional tests such as ultrasound (sonography) to check for causes of irregular periods.
Possible causes for irregular periods include:
- Ovarian cysts
- Uterine fibroids
- Opportunistic infections
- Unwanted weight loss
- Pre-menopause or menopause
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