Advertisement
The Body: The Complete HIV/AIDS Resource Follow Us Follow Us on Facebook Follow Us on Twitter Download Our App
Professionals >> Visit The Body PROThe Body en Espanol

Fact Sheet

FDA-Approved Anti-HIV Medications

Part of HIV and Its Treatment

August 2012

Antiretroviral therapy (ART) is the recommended treatment for HIV infection. ART involves taking a combination of anti-HIV medications (a regimen) daily. A regimen contains three or more anti-HIV medications from at least two different drug classes. Anti-HIV medications prevent HIV from multiplying in the body, which helps people infected with HIV live longer, healthier lives. ART may reduce the risk of transmission of HIV but anti-HIV medications can't cure HIV/AIDS.

The following table lists anti-HIV medications approved by the U.S. Food and Drug Administration (FDA) for treatment of HIV in the United States. The medications are presented by drug class and identified by generic name/acronym and brand name.


Drug ClassGeneric Name (Acronym)Brand NameManufacturerFDA Approval Date
Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs)
NNRTIs bind to and alter reverse transcriptase, an enzyme HIV needs to make copies of itself. Delavirdine (DLV)RescriptorPfizerApril 4, 1997
Efavirenz (EFV)SustivaBristol-Myers SquibbSept. 17, 1998
Etravirine (ETR)IntelenceTibotecJan. 18, 2008
Nevirapine (NVP)ViramuneBoehringer IngelheimJune 21, 1996
Rilpivirine (RPV)EdurantTibotec TherapeuticsMay 20, 2011
Nucleoside Reverse Transcriptase Inhibitors (NRTIs)
NRTIs block reverse transcriptase, an enzyme HIV needs to make copies of itself. Abacavir (ABC)ZiagenGlaxoSmithKlineDec. 17, 1998
Didanosine (ddI)Videx
Videx EC (enteric-coated)
Bristol-Myers Squibb
Bristol-Myers Squibb
Oct. 9, 1991
Oct. 31, 2000
Emtricitabine (FTC)Emtriva, CoviracilGilead SciencesJuly 2, 2003
Lamivudine (3TC)EpivirGlaxoSmithKlineNov. 17, 1995
Stavudine (d4T)ZeritBristol-Myers SquibbJune 24, 1994
Tenofovir DF (TDF)VireadGilead SciencesOct. 26, 2001
Zidovudine (ZDV, AZT)RetrovirGlaxoSmithKlineMarch 19, 1987
Protease Inhibitors (PIs)
PIs block HIV protease, an enzyme HIV needs to make copies of itself.
Atazanavir (ATV)ReyatazBristol-Myers SquibbJune 20, 2003
Darunavir (DRV)PrezistaTibotecJune 23, 2006
Fosamprenavir (FPV)LexivaGlaxoSmithKline, Vertex PharmaceuticalsOct. 20, 2003
Indinavir (IDV)CrixivanMerckMarch 13, 1996
Nelfinavir (NFV)ViraceptAgouron PharmaceuticalsMarch 14, 1997
Ritonavir (RTV)NorvirAbbott LaboratoriesMarch 1, 1996
Saquinavir (SQV)InviraseHoffmann-La RocheDec. 6, 1995
Tipranavir (TPV)AptivusBoehringer IngelheimJune 22, 2005
Fusion Inhibitors
Fusion inhibitors block HIV from entering the CD4 cells of the immune system. Enfuvirtide (T-20)FuzeonHoffmann-La Roche, TrimerisMarch 13, 2003
CCR5 Antagonists
CCR5 entry inhibitors block CCR5, a protein on the CD4 cells that HIV needs to enter the cells.Maraviroc (MVC)SelzentryPfizerAug. 6, 2007
Integrase Inhibitors
Integrase inhibitors block HIV integrase, an enzyme HIV needs to make copies of itself. Raltegravir (RAL)IsentressMerckOct. 12, 2007
Fixed-Dose Combination
Fixed-dose combination tablets contain two or more anti-HIV medications from one or more drug classes. Abacavir, LamivudineEpzicomGlaxoSmithKlineAug. 2, 2004
Abacavir, Lamivudine, ZidovudineTrizivirGlaxoSmithKlineNov. 14, 2000
Efavirenz, Emtricitabine, Tenofovir DFAtriplaBristol-Myers Squibb, Gilead SciencesJuly 12, 2006
Emtricitabine, Rilpivirine, Tenofovir DFCompleraGilead SciencesAug. 10, 2011
Emtricitabine, Tenofovir DFTruvadaGilead SciencesAug. 2, 2004
Lamivudine, ZidovudineCombivirGlaxoSmithKlineSept. 27, 1997
Lopinavir, RitonavirKaletraAbbott LaboratoriesSept. 15, 2000

This information is based on the U.S. Department of Health and Human Services' Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents.



This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
 
See Also
HIV Medications: When to Start and What to Take -- A Guide From TheBody.com
More on HIV Medications

No comments have been made.
 

Add Your Comment:
(Please note: Your name and comment will be public, and may even show up in
Internet search results. Be careful when providing personal information! Before
adding your comment, please read TheBody.com's Comment Policy.)

Your Name:


Your Location:

(ex: San Francisco, CA)

Your Comment:

Characters remaining:

 
Advertisement