Print this page
Back to Web version of article
FAQs About Treatment for HIV Treatment Veterans
January 12, 2012
Don't see your question? Ask it in our Choosing Your Meds forum or Managing Side Effects of HIV Treatment forum!
- Is it possible to re-use a regimen that has failed in the past?
- Is it possible for a person's virus to be resistant to every HIV med?
- Where are the new meds for long-term survivors?
- I'm about to begin treatment for the first time. Would it be possible that I have a strain that is already resistant to most meds?
- I have almost complete resistance to NRTIs (nucleoside reverse transcriptase inhibitors) and first-line NNRTIs (non-nucleoside reverse transcriptase inhibitors), and partial resistance to protease inhibitors. What are my options?
- I began HIV meds about 17 years ago. My resistance tests show that I am resistant to all protease inhibitors except Prezista (darunavir) and all NRTIs except Viread (tenofovir). My doctor put me on Norvir (ritonavir), Prezista, Isentress (raltegravir) and Atripla (efavirenz/tenofovir/FTC). Am I getting near the end of the road in terms of my options?
- I am one of those "forgotten patients" whose HIV is resistant to many meds -- even Isentress (raltegravir). I feel like the few of us left with multidrug-resistant HIV are going to be forgotten and die without help. What are the U.S. Food and Drug Administration and AIDS researchers doing for us, the forgotten few?
- I was recently diagnosed with HIV and had resistance testing done. The results show that, out of 19 different HIV meds, I'm already resistant to two of them: Sustiva (Stocrin, efavirenz) and Viramune (nevirapine). How can this be possible if I've never taken any HIV meds, let alone those two?
- I was infected with a strain of HIV that's resistant to the three major classes of HIV meds. My doctor has proposed a bunch of new medications and short-term use of Fuzeon (enfuvirtide, T-20) -- for only six months. Would stopping Fuzeon after six months make me develop resistance to it?
- After 12 years of HIV treatment, I have become resistant to some protease inhibitors, all NNRTIs and nearly all NRTIs. For the last year I've been taking Epzicom (abacavir/3TC, Kivexa) alone. I know that's not a good long-term strategy, but I seem to have few options. How can I find a drug combo that's effective and resistance-proof?
- I'm highly drug resistant, and my doctor just started me on a new, unproven drug regimen. If I become resistant to one or more of these new drugs too, what's next for me?
- I've heard that even if you are resistant to an HIV drug, that drug might still have some effectiveness. Is that true? Is drug resistance a matter of degree?
- I'm resistant to almost all HIV meds. However with two newly approved drugs, I was able to get my viral load below 200. Is that good enough or should I be striving to become undetectable?
- My HIV drug resistance test found no resistance to NRTIs or NNRTIs, but it did list a handful of "other mutations." What do these mutations mean?
- Does my decreasing CD4 count mean that I'm becoming resistant to my meds, even though my viral load is still undetectable?
- I stopped taking HIV meds almost two years ago, but now I need to restart treatment. An old resistance test showed resistance to a good number of meds. What are my options now?
- My CD4 count and viral load have been up and down on my current regimen. My most recent viral load was 190,000. Should I ask my doctor to switch me to something else?
- What are good HIV meds to change to in order to decrease my risk of another heart attack?
- Two months ago, my doctor had me switch to a new regimen containing six HIV meds, including two drugs I have resistance to. Before I started this new drug combo, my viral load was undetectable, and it still is now. My CD4 count has also gone up a bit. Why does my doctor have me take meds I'm resistant to?
- I am resistant to NRTIs (nucleoside reverse transcriptase inhibitors) and I've never taken a protease inhibitor or NNRTI (non-nucleoside reverse transcriptase inhibitor). My doctor wants me to try a new regimen consisting of Atripla (efavirenz/tenofovir/FTC), Selzentry (maraviroc, Celsentri) and Isentress (raltegravir). Is this a good combo for me?
- I'm planning to get rid of the protease inhibitors in my current regimen, and will replace them with the NNRTI Intelence (etravirine). However, I have drug resistance to the older NNRTIs. Does this switch still sound like a good plan?
- I've been taking Sustiva (efavirenz, Stocrin) for the past four years, even though I have resistance to it, because there weren't any other options for me. Could I replace the Sustiva in my regimen with Intelence? What other options do I have?
- I've tried several different HIV regimens for about 20 years. My viral load consistently hovers around 1,000. I'm worried I may have developed resistance to a lot of HIV meds. How do I decide which HIV meds to try next?
- My viral load seems to be increasing. I have resistance to some HIV meds and am about to switch to a new regimen. Is it realistic for me to reach an undetectable viral load again?
- I'm already resistant to a few HIV meds, and now my doc wants to switch me off of Fuzeon (enfuvirtide, T-20), which is keeping my viral load undetectable, to "save" it for later. Is this a good idea?
- My doctor has told me to discontinue using a fourth HIV drug because my CD4 count has risen to a healthy level and my viral load is now undetectable. Will I still be able to use this drug in the future?
- I'm currently taking four HIV drugs, and I want to switch to the three-drug combo pill Atripla. My doc doesn't think it's a good idea because my resistance tests keep coming back inconclusive. What do you think? Can I safely switch meds?
- I haven't missed a single dose since I started meds three months ago, but I'm being told I have "fossils" of resistance to some meds. What does this mean? Do I need to switch meds?
Resistance and Pregnancy
For frequently asked questions on other HIV/AIDS topics, click here.
This article was provided by The Body's "Ask the Experts" Forums.
You can find this article online by typing this address into your Web browser:
General Disclaimer: TheBody.com is designed for educational purposes only and is not engaged in rendering medical advice or professional services. The information provided through TheBody.com should not be used for diagnosing or treating a health problem or a disease. It is not a substitute for professional care. If you have or suspect you may have a health problem, consult your health care provider.