An Overview of Fuzeon (Enfuvirtide, T-20)
July 18, 2018
Brand Name: Fuzeon
Enfuvirtide must be given as an injection (a shot). Almost all people taking the medicine have a reaction at the location where the shot is given (called an injection site reaction). Injection site reactions with enfuvirtide are usually mild to moderate but occasionally can be severe. Reactions on the skin where enfuvirtide is injected include:
Contact your health care provider right away if you have signs of infection at an injection site (oozing, increasing heat, swelling, redness, or pain).
Enfuvirtide can cause serious side effects. These include severe allergic reaction and possibly pneumonia.
Contact your health care provider right away if you have any of the following symptoms, alone or in combination, that could be signs of a severe allergic reaction:
Contact your health care provider right away if you have any of the following symptoms that could be signs of pneumonia:
While taking enfuvirtide, it is important to keep all of your appointments with your health care provider.
What Is Enfuvirtide?
Enfuvirtide is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 6 years of age and older. Enfuvirtide is for people whose HIV infection is not well controlled by ongoing treatment with other HIV medicines. Enfuvirtide is always used in combination with other HIV medicines.
Enfuvirtide belongs to a class (group) of HIV drugs called fusion inhibitors. Fusion inhibitors block HIV from getting into and infecting certain cells of the immune system. This prevents HIV from multiplying and can reduce the amount of HIV in the body.
HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines (called an HIV regimen) every day helps people with HIV live longer, healthier lives. HIV medicines also reduce the risk of HIV transmission.
What Should I Tell My Health Care Provider Before Taking Enfuvirtide?
Before taking enfuvirtide, tell your health care provider:
How Should I Take Enfuvirtide?
Enfuvirtide comes as a powder that is mixed with sterile water to give as an injection (a shot). The enfuvirtide powder, sterile water, and everything else needed to give the injection come in a convenience kit. The kit includes:
Take enfuvirtide according to your health care provider's instructions. You or your caregiver should be trained by a health care provider before injecting enfuvirtide. Before using the medicine, make sure you understand the instructions for preparing and injecting enfuvirtide that come with the medicine. If you (or your caregiver) do not understand the instructions or are having a hard time mixing or injecting enfuvirtide, talk to your health care provider.
Enfuvirtide can be taken with or without food.
Always take enfuvirtide in combination with other HIV medicines.
If you take too much enfuvirtide, contact your health care provider or local poison control center (1-800-222-1222) right away, or go to the nearest hospital emergency room.
For more information on how to take enfuvirtide, see the FDA drug label from DailyMed. (DailyMed is a federal website that includes the most recent drug labels submitted to FDA.)
What Should I Do If I Forget A Dose?
If you miss a dose of enfuvirtide, take the missed dose as soon as you remember it. But if it is almost time for your next dose, skip the missed dose and just take your next dose at the regular time. Do not take 2 doses at the same time to make up for a missed dose.
What Side Effects Can Enfuvirtide Cause?
Enfuvirtide may cause side effects. Many side effects from HIV medicines, such as nausea or occasional dizziness, are manageable. See the AIDSinfo fact sheet on HIV Medicines and Side Effects for more information.
Some side effects of enfuvirtide can be serious. Serious side effects of enfuvirtide include infected injection sites, severe allergic reaction, and possibly pneumonia. (See the WARNING box above.)
Other possible side effects of enfuvirtide include:
Tell your health care provider if you have any side effect that bothers you or that does not go away.
These are not all the possible side effects of enfuvirtide. To learn more about possible side effects of enfuvirtide, read the drug label or package insert or talk to your health care provider or pharmacist.
You can report side effects to FDA at 1-800-FDA-1088 (1-800-332-1088) or online.
How Should Enfuvirtide Be Stored?
Where Can I Find More Information About Enfuvirtide?
More information about enfuvirtide is available:
The above Patient Version drug summary is based on the following FDA label(s): Kit.
[Note from TheBody: This article was originally published by AIDSinfo on July 12, 2018. We have cross-posted it with their permission.]
This article was provided by AIDSinfo. Visit the AIDSinfo website to find out more about their activities and publications.
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