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taurusthecat
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Supplement to help with depression/anxiety
#233538 - 11/11/07 07:49 PM
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Hey.
I don't really know where to post this, I thought that 'living with hiv' might be the best section.
I was reading the 'ask the experts' section and an anonymous poster asked one of the docs if there was any kind of natural supplement to help with anxiety. On the off-chance that this person reads this forum and for anyone else who cares, I found that a supplement which is a natural amino acid called L-TYROSINE works really well to deal with depression and anxiety. At least it has for me. You can find it at your health shop on the shelves next to everything else.
L-Tyrosine is a precursor in the body for dopamine, so helps with dopamine production.
I suffered from depression for about 5-6 years and went through about 5 different types of antidepressants with little or no success until I tried Prozac and settled on that for about 2 years. Early this year the Prozac stopped working effectively, I was starting to get grumpy and down, so I discontinued it and didn't feel any worse for it. While in my vitamin shop getting supplies I noticed a supplement on the shelf called L-Tyrosine and read the label and it said it was beneficial in aiding the symptoms of stress and anxiety so I bought some and gave it a try. I found it worked quickly and effectively in my case and gave me none of the mental 'fog' which I found with the Prozac. You take two a day morning and night and as far as I know it has no interactions with any meds or other drugs you might be taking. Taking this supplement has improved my mood to pre-depression levels, something which the traditional antidepressants never did, and I just wanted to share this with everyone, it's certainly worth a try in my opinion.
-------------------- I'm like fake fruit...... I don't bruise that easy.
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Hi, Taurus.
As someone to whom my specialist is dying to prescribe an anti-depressant, I was interested to read your post about L-Tyrosine - as I would consider taking something more "natural" or milder than the usual anti-depressants. (My partner was on anti-depressants for two years and we all observed how they shielded him from getting upset about things but at the same time he just didn't react normally to ANYTHING anymore. It was like there was a glass wall around him: great for protecting him against stress, but not good for us who wanted to reach him! Hence, I am very wary of going on anti-depressants.)
I've done a VERY brief bit of googling and found a coupl of things about L-Tyrosine. (Numbers in brackets refer to formal studies, so see the URL to examine the studies further.)
1. A rather impressively academic entry in Wikipedia states:
L-Tyrosine is sometimes recommended by practitioners as helpful for weight loss, clinical depression, Parkinson's Disease, Attention Deficit Disorder, and phenylketonuria.[citation needed]
Tyrosine is a starting material for neurotransmitters and increases plasma neurotransmitter levels (particularly dopamine and norepinephrine)[7] but has little if any effect on mood.[8][9][10] The effect on mood is more noticeable in humans subjected to stressful conditions (see below).
A number of studies have found tyrosine to be useful during conditions of stress, cold, fatigue,[11] prolonged work and sleep deprivation,[12][13] with reductions in stress hormone levels,[14] reductions in stress-induced weight loss seen in animal trials,[11] improvements in cognitive and physical performance[9][15][16] seen in human trials.
Tyrosine does not seem to have any significant effect on mood, cognitive or physical performance in normal circumstances.[17][18][19]
A daily dosage supported in the literature is about 100 mg/kg for an adult.[citation needed] The usual dosage amounts to 500-1500 mg per day (dose suggested by most manufactureres; usually an equivalent to 1-3 capsules of pure tyrosine). It is not recommended to exceed 12000 mg (12 g) per day.[citation needed] In fact, too high doses result in reduced levels of dopamine.[17] http://en.wikipedia.org/wiki/Tyrosine
2. Certain cancers, such as melanoma, depend on these amino acids to fuel their growth. Supplemental use of L-phenylalanine and L-tyrosine may raise or normalize blood pressure. Insomnia may occur from over stimulation if taken too close to bedtime. http://www.lef.org/newshop/items/item00326.html
BWB.
-------------------- Without a dream, life is a broken-winged bird that cannot fly. Keep hold of your dreams.
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taurusthecat
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Hey there BWB.
Always good to do research and find out all we can. I hadn't read that bit about melanoma, I'd only concentrated on the info I found concerning how it affects nervous function.
What I first read on the bottle label when I was in the store was this (I'm quoting direct from the label);
Helping to reduce the effects of mild anxiety and nervous tension. Assisting in the relief of nervous unrest. L-Tyrosine may be beneficial during times of stress as it assists the nervous system. It is also effective in supporting healthy brain and mental function and is known to assist with mental focus, improved concentration and cognition under stressful conditions.
I'm a bit of a supplement junkie, I've taken antioxidants for 20 years to help keep my skin clear, I take iron and folic acid to keep my hair from falling out, I take Lecithin to keep my cell membranes healthy and COQ10 to assist a palpitation problem I have with my heart and to help my mitochondria in all cells. When I saw what it said about L-Tyrosine I thought it was worth a try, when I stopped taking the Prozac because it was no longer doing it's job I was at the time getting very grumpy and anxious over the slightest little thing. What I read about helping to reduce anxiety and help to maintain mental focus really grabbed my attention so I bought it and gave it a go. In my case (and I can only speak for my own experience) I found not only was I more focussed and calm, but my mood actually improved as well and I was optmistic and relaxed. I stopped taking it for a few days and found I got grumpy again quite quickly, took it again and went back to normal. So for me it worked and I thought it was worth continuing. Even though I put my faith in supplements, they don't always work for me and I realise it when this happens. I tried DHEA to increase my energy levels and it made my heart wobble so I stopped, and I tried Valerian as a sleep aid and it actually did the opposite and made me edgy and I couldn't sleep. But in the case of L-Tyrosine I've really found it has affected my moods in a positive way after starting and stopping it a few times and monitoring the changes I feel during my experiments. I have in my case decided that it's definitely worth me taking.
-------------------- I'm like fake fruit...... I don't bruise that easy.
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Hi Pussycat!
Interesting to hear you've been on anti-oxidants for a good while. So have I. For 16 years in fact! My partner is a medic so he guides me in what is sound to take etc. We've both been taking anti-oxidants every day for those 16 years and now we look ridiculously young for our ages! Honestly. Foetus-face is what he calls me! So we believe they definitely work.
Interested to see you have not started taking ART. I take it you have your CDs monitored every 3 months? Have they never fallen dangerously low. If so, you're lucky. Mine fell below 200 within three years of my becoming infected and at the same time I had the most horrendous illness. They worked on the illness first, got me out of that, and then onto the ART, which I've been on ever since - with no further infections - except the normal odd cold.
And of course there have been the side-effects of the drugs. As I say elsewhere in my posts my side-effects to my first combination were serious, though rare (I was the "one in a thousand") but my side-effects to the second combination are just annoying.
I think my mild depression is due to the way that HIV has changed my life. It is no longer wise for me to be involved in the highly stressful work I used to do . . . and I miss it. While my HIV doctor wants to stick me on some anti-depressant to help me out of this, I believe it will be better for me to work my way out naturally, i.e. by doing healthy and creative things that give me a buzz and make me feel good. Unfortunately though, that takes a good degree of mental discipline . . . which I have to admit I lack! :-(
But I'm trying.
Best Wishes, BWB.
-------------------- Without a dream, life is a broken-winged bird that cannot fly. Keep hold of your dreams.
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taurusthecat
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Yeah, antioxidants are my friends, LOL. I remember the very first time I ever heard about them. It was in about 1988, I was watching TV and this program came on, a documentary about how some people were beating the aging process. It explained in great detail, very scientific, about how our cells are constantly being damaged by pollutants and that as each cell divides, the damage is repeated in both new cells and over time and many more cell divisions that damage is simply carried through and the result is what we largely see as 'aging'. Just the body breaking down and falling apart from the cells which compose it being torn to shreds by pollutants. Taking these antioxidants mopped-up the pollutants before they could get to your cells, and if you took enough of them, well - voila! You aged much slower.
I remember that program so well, it had a man and a woman who had been taking them for years pinching their skin and showing the cameras how elastic it still was. They said that skin age was determined by how quickly it snapped back into place when you pulled on it. So of course I went straight out and bought some and tried it out for myself. I'd just gone back to smoking at the time, I'd smoked since I was 16 and had managed to quit for about 6 months prior and my face had cleared up, all the blotches had gone and I looked wonderful. But in the weeks leading up to me seeing this program I'd gone back to it again and I'd quickly returned to having blotches and yellow skin tones and, well, not looking the best. It was just pure good timing and luck at the time that I saw this program when I did.
So I started taking the antioxidants, and like they had said on the show, I took a whole bucket more each day than they put on the label. I did my research and found out which vitamins were toxic and which ones weren't and made educated guesses on how many I could get away with taking each day and not ruin my health. That was before Selenium was included in the ones over here, it was illegal in this country for many years. So besides Retinol, all the others were pretty safe in large doses anyway. The two you have to monitor very carefully are selenium and vitamin A in it's retinol form, but beta carotene converts to A and is excreted when you have enough in your system anyway so they usually have that in them now instead.
After a few months I could see my skin clear again, the tone improved, I looked great again, but this time I was still smoking. I found that they really did work, they cleaned-out my skin/cells of a lot of the pollutants and had the same effect on my complexion as stopping smoking had months before. I was totally convinced and have taken them ever since.
And like yourself, I look young for my age and though I do slowly get older over time which is inevitable, it happens at an extremely slow rate. I don't go out all that much, but when I do and I go to the same bar and see the same people about once a year, I love seeing the jaws drop and looks of horror when they see I haven't changed at all. Gives me a real chuckle. The only thing I haven't been able to stop is the grey hair coming, but a bit of hair colour takes care of that.
ART I have just commenced in the last 2 weeks, I'm on day 14 as I write this. I've just been put on Kivexa and Nevirapine. I had some initial side effects to do with burning sensations in the lining of my mouth but they are subsiding now. I'm feeling wonderful already. Yeah, I got my blood checked every 3 months and my viral load was always somewhere in the tens of thousands and my t-cells around 450 or so. For 8 years the readings were pretty constant. I had one which shot up to over a hundred thousand viral load one time a year or more ago and the next one it was back down again and my t-cells only dipped down to 350 a couple of times. The last time they did I was so fed-up with seeing my body getting worse and worse, my energy levels in the pits, constant colds, skin breakouts of stupid fungal things and flaky skin which had no explanation, I was feeling like an old man and could only do a couple of things before collapsing into a chair and recovering. I kept seeing my t-cells in some magical "acceptable" level and felt like I was dying anyway. I had to plead for about a year to be put on something, tell them again and again that I had no quality of life and needed to give my body a break. My reasoning is that while it's distracted with the HIV, there are a thousand other things it's supposed to be doing but can't, every single little particle which enters our bodies has to be looked at, recognised, seen as friend or foe and then dealt with accordingly. I think I was just being swamped with so much incoming stuff in the form of bugs, bacteria, particles etc that my body was just collapsing under the strain. I had seen tiny little lumps all over my shoulders and chest for months and months, I just assumed I was getting older and my skin was going to pot, but in the last week they are disappearing and it's returning back to how it was before. I'm losing the bloated look I was getting and my energy levels are rising again, I can do a lot now and not get tired. Having HIV is more than just coming down with some fatal infection or cancer or lung condition or whatever and becoming fatally ill, it's your whole immune system being taken over and you just getting weaker and weaker as all the things it should be doing are ignored in favour of the bigger threat. At least that's what my experience has been. I'm over the moon now I'm doing something about treating it and knocking it on the head.
You mention how your depression may be connected to your HIV, and if I want to be honest with myself, I think mine is/was too. It didn't affect me until a couple of years after diagnosis, but if I really delve into it, I don't think I really acknowledged the reality of it at the time I was diagnosed. I think I was in a mild sort of denial for a couple of years. I just kept marching ahead as if nothing had happened, refusing to let myself be defined by anything such as an infection and putting it out of my mind as much as I could. I had already been given herpes at the age of 16 and had dealt with that for the whole of my adult sexual life, since the early 90's I had been taking acyclovir on a regular basis for it and I was very comfortable with having a virus living inside my body on a permanent basis, so when I was diagnosed HIV it didn't freak me out as it might have done to others, I didn't feel invaded or dirty or anything, I'd already gone through that stuff with the herpes 20 years before. It was initially more like "oh, another one, well 'hop on for the ride then' but be kind to me" more than anything else. But maybe I was just trying to laugh it off and be brave rather than let myself get frightened. The only thing that got me was thinking about my own death during the first 6 months all the time, which I found very distressing. It's just not natural for a 36 year-old to be doing that, it's something you expect someone in their 70's or 80's to be doing, not right when you're in your prime. I think that's probably the thing which affects us all the most. We're forced to face something like that all out of whack as far as timing is concerned and it plays with your mind and with your view of your life and your place in the world etc. I couldn't say "ahh... I'll get it done someday..." anymore, all of a sudden it was "oh, crap, there might not BE a someday! I better get started on anything I ever want to do". I remember I felt a great deal of urgency in getting things done in my life, like a cracker had been shoved up my butt, which was probably a good thing because I always was a big procrastinator. I still do feel that urgency, but it's subsided a fair deal.
But in relation to the depression, it wasn't until about 3 years after diagnosis when I had left my partner and was on my own, living in a rented house and not making ends meet and then getting laid off from my job and finding myself with no income and then at the same time having a whole bunch of losers come into my life and ruin what was left of it that I totally lost it and had a massive breakdown. And by that time no amount of positive thinking or doing healthy and creative things was going to work for me, medication was the only option in order for me to be able to function and not kill myself. I got so bad I couldn't hold a conversation, my mind was blank at the slightest hint of stress, someone would ask me a question and I couldn't answer even the simplest thing. If I was in a social situation and someone was making small talk, I would just have these thoughts running around like mad in my head "I know I'm supposed to say something..... I can't think what to say....." I would struggle and struggle for anything to say, my mind just was blank and I couldn't come up with anything coherent, and this was from someone who used to be the life of the party, always a quick response, able to put people at ease etc. Depression decimated me. I withdrew into myself and became a vegetable in my own world a lot of the time. The saving thing for me was when I was allocated a home of my own by the government, a small one bedroom bungalow with a front and back garden in a quiet place. I had become homeless and was living in a rooming house filled with cockroaches and drug addicts and foot fungus and had no kitchen of my own, no shower, no toilet, only one little room with a crooked single bed a few people had probably died in. When I finally got my own place I shut that front door and locked myself away for about a year and healed myself.
My problem was largely that I wasn't able to say no to people and had let people come into my life and alter it to suit themselves, I just wanted to please. I was too sensitive and a slave to what was going on in my environment at any given time. Too easily affected by my surroundings. Through a lot of healing and closing myself off from the world I learned that most of what had pushed me to depression was just not being, or feeling at least, in control of my own life. Once I was able to control who came into it and have absolute and total say over who came in my front door and how long they stayed there, I started to regain myself and heal. I did a lot of spring cleaning and removed just about everyone from my life because they were all toxic for me. In the year I was healing I worked out who I was now and what was important to me and rather than see the good in everyone and accept people at face value and forgive their bad behaviour, I gave myself total permission to say "if they aren't good for me, they aren't coming through that door." I ditched friends old and new, family, whoever I felt didn't care about my feelings or suffering and even though it was basically everyone I knew, I was happier having no-one in my life than even one person who was toxic for me. I started fresh and gave myself permission to know that even though everyone has a good side and everyone is basically right in their own way, for me it's OK to say "I don't like that person or how they treat me or how they behave and it's OK for me to not want to know them." Before I could never have done that. I felt I had a moral obligation to accept everyone on some level and if I said "go away" to someone I was being a selfish and bad person. I learned a lot in that year.
I think that all of us who suffer from depression can do a lot to combat it by taking back control of our lives and feeling able to say "no" more often. For me it was the feeling of losing control over my life which pushed me over the edge to begin with and kept me down in the pits of hell for about 5 years.
That's also why beginning ART is something which has made me feel even more empowered, the last thing that had me by the balls was the virus, going and having it monitored month after month, year after year was soul destroying for me when I could see and feel it killing me but could do nothing about it because my t-cells hadn't fallen below some magical pre-determined level. That made me so angry and frustrated. I really think they need to get off their arses and realise that it's the viral load which is the killer, not how well your body is or isn't coping with it. This "it isn't below the required level yet, see you in 3 months time" approach just made me feel frustrated, futile and angry, while I felt my body and quality of life slowly slip away.
BWB, if you are feeling moderately depressed, even without knowing you or your particular situation, I would say to you find anything and everything that annoys you and vexes you in your life, people, situations, things, whatever, no matter how small you think it is or how trivial, and give yourself total and utter permission to do something about removing or fixing them. Take away all stresses for the sake of your own well-being, if it's people show them you mean business and be clear in what you need them to do, I was ruthless far beyond what most people would feel comfortable doing, you don't have to completely cut people out of your life, but do bear in mind that each and every little annoyance will eat away at you and join together to make a burden which will depress you more and more. If you feel you are in total control of your life and what happens in it, even in relation to the HIV (which I really think we all need to make friends with, not fight, like the herpes, if it just lives in you and doesn't hurt you then it shouldn't be cause for stress, you can co-exist in peace maybe), you feel empowered and strong and those feelings go completely against the grain of depression. They help to cancel it out and heal you.
I also have noticed that those of us who suffer from depression seem to be more caring and sensitive to others than the rest of the world a lot of the time, we care too much at times it seems and work ourselves up into a mess, it seems like we take on the world's problems and everyone's in it onto our own shoulders. No wonder we get stressed and depressed. Try caring a little less, or at least diverting some of that special care to yourself. I have seen in myself and with alarming regularity in others who suffer this insidious condition that we always tend to put ourselves last on the list and that needs to change if we are to feel better in ourselves. It won't make you a horrible person if you think more about what you want and your own well being and less about others. Try it.
Just my thoughts on it.
Taurus.
-------------------- I'm like fake fruit...... I don't bruise that easy.
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That was a great post, and I will add that it helped me too. D
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taurusthecat
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I'm glad Florida. :-)
-------------------- I'm like fake fruit...... I don't bruise that easy.
Edited by taurusthecat (11/22/07 08:09 PM)
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Hi Puss!
I hope Melbourne's lovely today!
Well, I have just read your whole email. Quite a story.
My god, YOU know what depression is. I have never been to the depths that you have, i.e. being speechless etc in company and so forth. This is what I would guess is termed "clinical depression", i.e. really really deep depression. And I do believe that for a situation like that taking a drug to kick-start the getting-out process is valuable. It helped get you to a place where you could at least begin to exert some control over those negative influences in your life. You call them "toxic". I call them "crazy pavers" - people who appear out of nowhere and proceed to lay an f'ing concrete pavement right across your path in life. They're a menace. They have to be got shot of. I'm good at that. Always been good at it. What I have to do at the moment is start reaching out again - otherwise there ain't gonna be hardly anybody at my funeral! LOL! But I find it difficult to reach out knowing that I AM a kind of imposter in that I am not going to tell people I am HIV until they become exceptionally close friends, and quite possibly I will never tell them. So this makes it difficult. Anyway, I'm happy enough with our things are going.
I got a CD4 count of 570 yesterday! My highest since that drop below 200 a couple of years back when I got seriously ill. So my stress levels HAVE probably been improving.
I know what you mean too about suddenly being confronted with thoughts of death etc. It hits me every morning as I open that blasted plastic tablet-box and take out another three to drop inside my gullet. And every 9 days the tablet-box needs re-filling. How long will this go on for, I ask. Forever! comes the reply. Jesus! I need air, I need food, I need sleep, and I need these damned tablets. But for how long will I do comparatively well on them, as I am? I know that one day there's going to be a complication. That's depressing. On the other hand, I see that so-and-so a celebrity has just died of cancer at 43, and so forth. So then, I think, well, I haven't had too bad an innings really. And then I resolve to just try and make more of the good days that are left. They could last for years and years. Or they might not. I would be a bit annoyed if they lasted for years and years and I looked back and saw that I had not made the most of all the extra time that these ART drugs had given me.
Anyway, once again, nice to read your thoughts. Impressed to hear how you have climbed out of a horrible hole of depression and are now much better placed.
Best Wishes, BWB. (freezing right now in my part of the UK!)
-------------------- Without a dream, life is a broken-winged bird that cannot fly. Keep hold of your dreams.
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taurusthecat
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It's freezing in the UK right now is it? I bet you can't wait until February arrives then. I lived in London from 1990 to 1998 and had to get used to the cold winters, not like the winters here in Melbourne really, here they are damp and soggy and pretty mild, there they were as crisp and dry (and cold) as an industrial meat refrigerator. But I got used to it and loved it anyway. I even went with a boyfriend I had once to see a friend of his who lived in Aberdeen and we spent some time in Edinburgh as well, we went at the beginning of Feb, now THAT was COLD!!! Woah!
Right now here we're in the last weeks of Spring when the weather starts to heat up in earnest, we've had a few days of over 30 deg Celsius already. We've had the worst drought on record for a few years now and we've been on water restrictions all year, but in the last two weeks we've had some decent rain for a change here and there and yesterday and today a cold change came over and it plummeted down to 14 and it's soggy and cold again and wetter than it's been in ages. That won't last and we're due for a clear sunny and hot week to come.
Great result re your t-cell count, 570 is excellent! I'm actually going to my doc tomorrow for the first check up since beginning my medication and I'll have a blood test taken to see how the viral load is going. That's what I'm most concerned about and am interested to see. I noticed a whole heap of little subtle changes in myself over the last 2 weeks and I feel better than I have in ages already so I am thinking that it's already dropped quite a lot already. Can't wait to find out.
As I've written before either in this thread or elsewhere, I take suppressive therapy for herpes and have done for 20 years which is one pill per day, also I take 6 antioxidants, 2 iron and folic acid, 2 lecithin, a somac for acid, a L-Tyrosine for my mood, 2 COQ10 pills for my heart, a multi vitamin for minerals and if I'm having a headache two paracetamol for that. Now I have three more to add to the pile! I rattle when I walk away from the sink after swallowing them all. But I don't get upset, I look at them as my friends. Especially these new ones, I pretend they are little combat soldiers when I see them in a row in the plastic pill box and say hello to them and thankyou for being there. (I talk to plants and insects too, LOL.)
Now I have had this virus for a while I realise that thinking about what it might ultimately mean to my body is not productive, so as soon as any morbid thoughts enter my head I instantly try to divert/distract my attention and move my thoughts to what I have to do next, like chores, phone calls, upcoming outings or whatever. It serves me no purpose to dwell. As I said, I was constantly faced with the issue of my own death for the first 6 months to a year, I can't really remember how long it went on for now, only that it was extremely distressing. But it wore off after a while, I think my subconscious just got sick of it and calmed down, but I had no control over the process. All I can say to you is that it will go away in it's own time and you just have to be patient and put up with it like you would any other annoyance. It will go away sooner or later. The pills won't, but just try to see them like any other medication, like if you had high blood pressure and had to take a pill for that. No big deal.
You are totally right when you say you may look back and see that you haven't made the most of the time you had, but we do that anyway, HIV or no HIV. Just try to distract your attention away from your health as long as it's under control and concentrate on whatever it is you're up to in your life. Make as many grand and exciting plans as you can for this year, the next year and the ones after that and focus on those. Me, I've got a few music projects keeping me busy and they will keep me involved for several years and then when they're coming to a close I'll just think up some more goals to work towards. No time to die right now, LOL. Too much to get done.
I'm actually jealous of you at the moment. I want a white Christmas too. I'm sick of flies and hot sticky nights where you can't sleep over the festive season. Just once more I'd like to look out the window on Christmas Eve and see the same scene outside that's on my Christmas cards, all that snow and stuff. It's so romantic and trad. I'd love to get back over there in a couple of years time for the holiday season, might make that one of my plans.
Hugs,
Taurus
PS I'm totally in love with that "crazy paver" term and analogy of yours. Too cool.
:-)
PPS In regards to you not telling people your status and feeling fake about it in some way, would you tell everyone you met and knew that you had piles? Sorry to be crude, but in my mind HIV is no more relevant an issue than having any other medical condition is. If I had piles I would keep it to myself and still feel like my friends and acquaintances 'knew' me. You're not in any way being an imposter. You're you. Don't worry about it.
-------------------- I'm like fake fruit...... I don't bruise that easy.
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taurusthecat
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Went to the doc and it turned-out that I don't get blood taken until another two weeks has passed at the one month mark. But I filled him in on how much better I'm feeling and what sort of issues I've had the past 2 weeks. I'm still none the wiser as to my viral load and how it's going, but guess I'll just have to sit tight and wait a bit more to see.
-------------------- I'm like fake fruit...... I don't bruise that easy.
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