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New vaccine shows promise!!!!!
      #118453 - 11/29/04 11:58 PM

Novel Vaccine Activates HIV Immunity, Slows AIDS Virus
Monday, November 29, 2004
By Daniel J. DeNoon

It worked in mice. It worked in monkeys. And now in humans, a therapeutic vaccine has stopped HIV in its tracks.

The vaccine is made from a patient's own dendritic cells (search) and HIV isolated from the patient's own blood. Dendritic cells are crucial to the immune response. They grab foreign bodies in the blood and present them to other immune cells to trigger powerful immune system responses to destroy the foreign invaders.

HIV infection normally turns these important immune system responses off. But animal studies show that when dendritic cells are "loaded" with whole, killed AIDS viruses, they can trigger effective immune responses that keep infected animals from dying of AIDS.

Wei Lu, Jean-Marie Andrieu, and colleagues at the University of Paris in France and Pernambuco Federal University in Recife, Brazil, tested the vaccine on 18 Brazilian patients. All had HIV infection for at least a year. Their T-cell counts — a crucial measure of AIDS progression — were dropping, meaning their disease was worsening. None was taking anti-HIV medications.

After getting three under-the-skin injections of the tailor-made vaccine, the amount of HIV in the patients' blood (called the viral load) dropped by 80 percent. After a year, eight of the 18 patients still had a 90 percent drop in HIV levels. All patients' T-cell counts stopped dropping.

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Re: New vaccine shows promise!!!!! new
      #118556 - 11/30/04 05:39 AM

This would be wonderful news if it continues to show further promise and progression with being able to slow down/stop the progression of advanced hiv/aids...What a GREAT wish that would be to have come true...=)~Jessie~

HIV+ since 2-3-04
"While there is breath, there is hope".

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Re: New vaccine shows promise!!!!! new
      #118931 - 12/02/04 02:59 PM

I showed my hiv doc this and he said that there are several of these trail vaccines going on now....There is GREAT hope and promise that they will find a vaccine in the near future that either will slow down the process of the virus or be able to elimate the vl from increasing and keeping it at an undetectable level which in turn will help the bodys own defense against fighting the hiv virus....This is very promising and encouraging as well...Thanks for your post....~Jessie~

Hiv+ since 2-3-04
"While there is breath, there is hope".

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