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Window period
      #30869 - 03/30/02 06:32 AM

Can Anyone show me medical evidence that 3 month elisa is conclusive?

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Re: Window period new
      #30873 - 03/30/02 06:51 AM

what are you kidding me? do you think they are guessing? They have been studying HIV for 20 years, don't you think they have seen the medical evidence by now? the CDC would not put out testing guidelines without knowing for sure. and don't forget that they are, thankfully, EXTREMELY conservative at all times.

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You will be dissapointed new
      #30876 - 03/30/02 08:56 AM

Unfortunately you are asking too much.

There is no evidence in medicine to be 100% of anything, and that includes every other thing not just HIV.

Doctors today, and particurarly in US WILL NOT give you anything as evidence and concrete due to fact they can get sued.

I remember reading Dr Joel Gallant answer to something in which he states that in last few years there were 8 cases of false positive test - and each one of them ended at court.

So, doctors will not give you guarantees for 3 months, they will alsonot give you guarantees for 6 months, or 1 year or five years - they will always say 99.99%.

So, stop searching for something you can't get - but loook from the other perspective.

HIV specialist around the world are claiming that all people will show positive result by 3 months. The whole Europe, UK and Australia are working exclusively on 3 months window period. You ring CDC of those countries and they will tell you 3 months is conclusive - I did it in Australia and I know other people did it in Sweden and UK.

IN Australia or Europe we don;t have that many courth cases over everything as they exist in US - and that is the fact. I am not saying here right or wrong I am just stating the facts.

Getting back to your answer there is no 100% in everything, even if person test positive on Elisa - that's not 100% - they than do Western Blot to confirm, if that is positive than they do viral load if that is positive the case is confirmed.

Clinicians agrees that at least two positive result has to be there in order to prove one being infected - so that is also not 100% with Elisa test.

You also have to visit the site of New York State Health Department - in which they claim that 3 months is conclusive.

And at the end every rule has something out of rules - but it is so rare that the official institution do not want to change gudilines for such rarety.

Hope this observation helps, and if I was you I would put the same question to Ryan Kull - who wil probably answer along the line that we have enough experience with newest test and particurarly PCR tests that we now now that everybody will seroconvert in 3 months time.

Ask him. I am sure he will answer that as it is very chalanging question.

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Jamie LEE

      #30882 - 03/30/02 01:01 PM

This is very current and will make you feel better!!!

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Jamie LEE

      #30883 - 03/30/02 01:03 PM

Thinking about an HIV Test?
Provided by Stephen Fallon, Ph.D.
© 2002 Stephen Fallon

Summary: If you wait just a little while after engaging in a risky behavior, you can then get a reliable HIV test. Wait three weeks, and a negative HIV test result is very reliable; wait three months, and it's virtually 100% accurate. Some local health departments require a person's name for testing, which is kept in confidential files. Others provide anonymous testing services; no one knows your name; you get an identification number to bring back for your results.

How do the tests work? Each year, 25 million Americans are tested for HIV antibodies1. Only certain sites are authorized to perform anonymous tests. The most common way to test involves drawing a small sample of blood. Some providers can also do a test with just a swab that collects saliva and mucosa from your mouth. Soon a new test will screen urine for HIV antibodies2. It's important to remember that saliva and urine do not transmit HIV. These tests are measuring your body's counterattack on HIV (antibodies), not actually finding HIV particles.

All tested fluids are first checked using an inexpensive test, such as the ELISA or Synthetic Peptide test. If the test produces a positive reading, this result is double-checked with a much more specific test, such as the Western Blot.

Are those tests really accurate? You may have heard about problems with early versions of HIV tests, which gave many people inaccurate test results. But tests have been improved. In 1990, 1.5 out of every 100 tests gave a "false positive" result, meaning that the test thought you had HIV when in fact you did not3! But by 1997 the false positive rate had dropped to less than 5 out of every 100,000 tests for the ELISA, and the Western Blot would rule out even those few false results4.

What is the "window period of uncertainty"? Standard HIV tests screen for your antibodies to HIV. Most people begin producing antibodies within a few weeks, although a few may take several months. So if you rush to a clinic for a test too soon after a risky behavior, you could receive a "false negative" result, suggesting that you're not infected when you actually are.

Fortunately, the "window period" has been cut as tests have improved. In 1990, the ELISA test provided reliable results only if the person's risk behavior had occurred six weeks ago (95% accuracy at 45 days). Today, improved tests give highly accurate results just three weeks after any risk behavior (95% confidence at 25 days5, or even 22 days6 ). Still, a follow-up test is required to approach 100% accuracy. Nearly all patients seroconvert (i.e. possess detectable antibodies) by three months after their reported risk behavior7.

This is very current and will make you feel better!!!

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