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4th gen test p24 again
      #192397 - 05/20/06 10:06 PM

seems to me the so called 4th generation test is only good up until 3 weeks after infection. all the research i have done says the p24 antigen test is only good 1-3 weeks after one would have been exposed. so this would mean if i tested at 6 weeks with the 4th generation combo test the p24 test would not be any good for diagnosis.

i have also called Massachusetts' aids hotline and asked about the test they use and they told me it was a standard antibody test and not the so called 4th gen test which makes sense because 6 weeks is too long to wait to test with the p24 antigen test since it is only good up until week 3 and after that the antigen p24 is gone and antibodies are present.

i think some people have their fact wrong on this subject and invite everyone to research it themselves.

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Reged: 07/19/05
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Re: 4th gen test p24 again new
      #192403 - 05/20/06 11:28 PM

You know, I think we're all taking a simple concept and making it way too hard.

The CDC says 97 percent of infected people will test positive within 3 months. (Someone said this figure is based on "old data" and that the percentage is higher now. I'm not sure how they know that, but I'm willing to buy 3 months as a definitive window period.)

Dr. Bob in the prevention forum on this Web site also uses the 3-month standard, as do most public health departments -- Massachusetts notwithstanding. (I asked my earlier question about the Mass. window period because I wanted to see how they phrased it, but it was ultimately not very illuminating.)

I think we all should drop this folderol about 4th generation ELISAs, P24 antigen tests, whether Massachusetts uses a different test or not, PCRs, blah blah blah. All this just blurs the bottom line, which is: Get a standard antibody test at 13 weeks. That's the ONLY test suitable for a definitive result.

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Re: 4th gen test p24 again new
      #192473 - 05/21/06 11:08 PM

I called the AIDS helpline in Massachusetts a few weeks ago also and I asked them if they used a more up to date HIV test and they said no, they use the regular the HIV Elisa antibody that's used in the US.

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Re: 4th gen test p24 again new
      #192655 - 05/23/06 12:06 AM

that is because they don't use a 4th generation test and if they did the window would be 3 weeks

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