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Lipodystrophy and WastingLipodystrophy and Wasting
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Steriods fight waisting?
Dec 10, 2001

I scoured previous Q&A trying to find your thoughts on using steriods to help fight wasting. My counts are all good (VL undect- T 600+) yet I'm seeing loss. I'm a slight person and am getting slighter. Whats the harm vs benefits of using steriods to improve my muscle mass? -Jeff

Response from Dr. Fisher

The data on anabolic steroids is fairly extensive. A number of studies have been done with several agents, oxandrolone, nandrolone, oxymetholone in patients with HIV-associated wasting. In general the studies have shown improvement in muscle mass over 3-12 months of treatment with minimal side effects. Exercise (resistance exercise) potentiates these effects. No clear evidence on using anabolic steroids (or for that matter any agents) to combat fat wasting in lipodystrophy however. There may be an exacerbation of insulin resistance, increase in LDL-cholesterol, decrease in HDL cholesterol. But these can be monitored (and exercise should help). Anecdotal evidence suggests that even longer courses of therapy (more than 12 months) are safe and may help in maintaining weight and muscle mass. Good luck in your efforts. Talk to your doctor. AF

FDA says they will consider new-fill for those who have started treatment
Current status of new-fill

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