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Lipodystrophy and WastingLipodystrophy and Wasting
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Ephedrine and Clenbuterol
Sep 7, 2000

Dear Doctors,

Can you tell me what Ephedrine and Clenbuterol does to the human body ?

I have heard that these medications are anabolic for muscle and catabolic for fat-mass.

Is this a good medication to combat muscle wasting and fat gaining ?

I've heard that it is bad for the heart, but i have a healthy heart, and i am only 25.



Response from Dr. Hellerstein

You ask a good question. We know more about what these medicines do to animal bodies (sheep, rats) than humans, it turns out. But we can say a few things that might help you.

These are adrenalin-like agents. They stimulate calories to be burnt, fat to be broken down, and (in animals, maybe less so in humans) some muscle to be gained. The effects in humans, in limited studies, have not been very impressive, however (only a couple of pounds of weight loss and minimal effects on muscle mass).Also, some studies have shown side-effects (tremulousness, nervousness, other adrenalin-type symptoms).

There are also adverse effects on blood pressure and perhaps other cardiovascular risk factors.

All in all, the studies have been disappointing. Drug companies in the U.S. have therefore pretty much given up on these agents, in their current forms.

If your main problem is muscle wasting, these are certainly not the best options available. For fat gain, there are also better established treatments.

All in all, it's hard to give an enthusiastic recommendation for these (unapproved) agents.

Good luck,


I need some advice
Dieting with HIV

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