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Lipodystrophy and WastingLipodystrophy and Wasting
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Apr 19, 1999

What is lipodystrophy and what are the signs and can it be prevented?

Response from Dr. Fisher

LD has not been specifically defined but includes the following manifestations: 1. fat redistribution..."buffalo hump" or "protease paunch" due to fat accumulation; breast enlargement in women. Facial or arm/leg/butt fat wasting. 2. hyperlipidemia...high levels of blood cholesterol and/or triglycerides 3. insulin resistance occasionally associated with high blood sugars (and maybe diabetes)

We don't know if it can be prevented, but proper attention to diet, exercise, testosterone replacement when indicated, anabolic agents for lean body wasting...may be helpful. ALso using protease-sparing regimens (with sustiva or viramune) if appropriate can delay or prevent LD.

Alvan Fisher, M.D.

does dhea helps against lipodystrophy
Oxandryn used for

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