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Lipodystrophy and WastingLipodystrophy and Wasting
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A definitive answer for wasting?
Aug 5, 1999

Hi, Do you have some idea when they will get to the bottom of why people with AIDS are experiencing the loss of fat in their face, arms, and legs? Is there a serious effort to solve this riddle? I read recently that in the case of D4T, it has to do with mitochondrial toxicity. Is this the case with all the AIDS drugs? Also I heard touted that HGH can help reverse this problem. Unfortunately most people don't qualify to receive this outragously expensive drug for one reason or another. This condition, wasting, causes alot of psychological pain for us who are lucky enough to have survived AIDS thus far. Have you any insights on the research that is being done???

Response from Dr. Fisher

This problem is very complex and unlikely to have a simple cause. Check out the information available from the recent conferences...HIV/nutrition, Cannes, April, Lipodystrophy workshop, San Diego, June...information widely available on the net (and from links at Also recognize that the major advances in HIV/AIDS treatment that we have seen in the last few years are almost exclusively due to advances in antiretroviral that is where most of the clinical research has been directed. Alvan Fisher, M.D.

lyphidostrophy (sp.?)

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