|METFOMIN FOR LIPODYSTROPHY
Aug 5, 1999
I WAS TOLD THAT LIPODYSTROPHY CAN BE REDUCED BY TAKING METFOMIN 500 MG BID OR TID
COULD YOU ADVISE WHETHER THIS IS HELPFUL
THANK YOU FOR YOUR ASSISTANCE
WITH WARMEST REGARDS
Response from Dr. Fisher
Metformin is an insulin sensitizer used in people with type I and type II diabetes. Because the diabetes in HIV associated with lipodystrophy is known to be due to insulin resistance, the use of metformin or troglitazone (and other related drugs) has been and is being investigated. These drugs are certainly helpful in treating the diabetes associated with HIV...but I'm not aware of evidence that they help the other manifestations of lipodystrophy. Alvan Fisher, M.D.
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