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High levels of Creatinine Kinase enzyme in the blood
Mar 1, 2000

Thank you for this forum! The KClevels in my blood have been between 1300 & 1400 since I was first diagnosed HIV+

and Hep-C. I'm on Combivir and Sustiva. The KC levels were

1400 before I started on AZT and have stayed high for the

six months of treatment. Viral load was 800,000[now 50 and

CD4 was 120[now 490]. I was doing much better for a while

but now I'm losing strength in my arms and legs and neck. I

can hardly make it up three or four stairs and a 2 litre

milk bottle is almost too heavy to lift. If AZT is not the

problem can anything be done to lower the KC levels and if

not - ?

Response from Dr. Dieterich

CPK levels that are that high are often symptomatic of myositis or muscle inflammation. If it was elevated before AZT, then it is not the AZT. You may have a muscle disease unrelated to HIV. You should ask your MD to consider muscle illnesses and do the testing for things like polymyositis. Douglas T. Dieterich, M.D.


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