Thank you for this forum! The KClevels in my blood have been between 1300 & 1400 since I was first diagnosed HIV+

and Hep-C. I'm on Combivir and Sustiva. The KC levels were

1400 before I started on AZT and have stayed high for the

six months of treatment. Viral load was 800,000[now 50 and

CD4 was 120[now 490]. I was doing much better for a while

but now I'm losing strength in my arms and legs and neck. I

can hardly make it up three or four stairs and a 2 litre

milk bottle is almost too heavy to lift. If AZT is not the

problem can anything be done to lower the KC levels and if

not - ?

CPK levels that are that high are often symptomatic of myositis or muscle inflammation. If it was elevated before AZT, then it is not the AZT. You may have a muscle disease unrelated to HIV. You should ask your MD to consider muscle illnesses and do the testing for things like polymyositis. Douglas T. Dieterich, M.D.