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wrong virecpt dosage
Feb 5, 1998

I was told to ask this ? again by JC to get a second opinion.. let me preface the question by telling you that I have not switched my combo yet...

Doc, I am frustrated .. I have been taking Virecept three times a day but only 1

250 tab ( I mistakenly read the dosage wrong) I know I should have been taking 3 tabs

3 x a day ( 750 mg) Now what?.. I have been udetectable for 9 months with this

uncorrect dosage regime .. and now my third viral load shows 3824. Should I start

taking the correct Virecpt dosage and retake a viral load in one month and see if goes

back to undectable or should i switch everthing now. ( I was drug naive before

starting my cocktail) Please give me some advice..thank you!

Response from Dr. Gallant

I'm going to answer this even though it was marked for Dr. Currier, since it sounds like you're asking for a second opinion.

I agree with the first opinion. How you deal with Viracept resistance when it occurs is the same no matter what the reason was for it happening. What happened to you is unfortunate, but it's not an unfixable problem. In people failing Viracept for any reason, I usually recommend ritonavir/saquinavir plus a complete change in RT inhibitors. There's good and growing evidence that this approach works.

Good luck!

Joel Gallant, M.D., M.P.H.

Despairing over PI related facial muscle loss
Viracept and Cross Resistance

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