Oct 29, 1996
I have a friend with aspergillus in his sinuses; it may have now moved into his brain. I'm having a hard time finding out more information about this infection and prognosis.
Response from Dr. Cohen
Aspergillosis is a relatively rare fungal disease in people with AIDS, but when it does occur, it can be quite severe. It usually presents as lung disease in people with advanced HIV disease, but it can also involve the sinuses, where it be invasive and spread to surrounding areas.
The drug of choice to treat aspergillosis is amphotericin B, which is an intravenous medication. Itraconazole, an oral antifungal drug, can also be helpful. Unfortunately, when it is invasive, aspergillosis can be difficult to treat even with the best medical therapy, and it often carries a fairly poor prognosis.
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