|My first blip?
Jan 21, 2002
Hi doc My question is: I have been on azt,3tc,crixivan since 1995 when crixivan was in trial i never had change my combo or mised a dose? till today! Im also been on Remune for two years and did the (Z gene therapy)no plasebo.plus one siclo of il2. yes I did alot staff for my self. and I always been undetectable since 1995. under 500 first and with the new ultrasensitive tests under 20. for the las almost 7 yrs. my cd4 allways 700 to 1100, and my cd4 29 to 42. now 32 cd4 798. my question is I have my last lab test result showing my viral load 126?? its a blip i know! i should be worry about resisten? the test was the ultra sensitive under 20! its the first time a test show me hiv in my body!! hope you can healp! thanks.could be a wrong result? i was with a cold at that time? its normal? thanks very much for your healp. Rob.
| Response from Dr. Young
Thank you for your question.
Very low viral load testing, particularly when preceded by undetectable viral loads are usually "blips". This is typically defined by a return to undetectability in the next several weeks.
We are many theoretical causes of blips, from misses doses of medications to low level immune activation-- as accompanies cold sores or vaccination.
We know from several studies (see Havlir, 2001; Sklar, 2001) that there does not appear to be any signficant risk of the emergence of resistance and/or drug failure from blips.
With viral loads less than 1000 copies, it is not reliably possible to get a viral genotype or susceptibility test to assay for resistance. Best advice is to just get the viral load run again after a few weeks (provided that you aren't sick or have missed doses). Good luck, BY
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