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CD4 of 44 can climb to???
Jun 30, 2008

If starting treatment at CD4 44, what level can be reached if meds are taken religiously and no resistance comes about? Is 200 reachable? Is 500 reachable, which seems to be the "normal life expectancy" threshold?

Response from Dr. McGowan

I love the optimism in your question. The answer is a good one. Most people are able to increase their CD4 counts significantly as long as their virus stays suppressed. This is called immune reconstitution. Achieving CD4 counts over 200 or 500 can be expected for most people. Some factors that effect the overall response are: the lowest value that the CD4 count has fallen (lower values may be slower to improve), the age of the person (age over 50 may have a slower increase), other active infections or conditions (presence of TB or other opportunistic infection), history of chemotherapy that may effect the bone marrow, nutrition, maintaining consistently suppressed viral load, and time. A number of studies have shown that CD4 counts can be expected to continue to increase for several years, so as long as the trend is going up just keep riding it as high as you can go.

Best of luck, Joe


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