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trouble with meds
Jun 30, 2008

ive been positive for almost 4 years now. i started strong with my meds, took them like i was supposed to, but as time went on i started taking them less and less. i to my last blood work said i was still undetectable, i was a little surprised. i started back on my meds, but im a little worried about resistance and such. the doc says im fine, but still i worry. what do you suggest that i do?

Response from Dr. McGowan

Intermittent adherence to HIV medications is the major reason for the development of HIV drug resistance. So you are right to have been concerned. However, it appears from your description that in spite of intermittent adherence your viral load remained undetectable. As long as you are back on your medications and your doctor is periodically checking your viral load to make sure it remains undetectable, there is no reason to assume that you have developed any significant drug resistance. The virus develops mutations one at a time. It may take a certain critical number to accumulate for the viral level to start to increase. It is best to try to prevent this from happening by keeping the virus fully suppressed by not missing any doses. You do not want to open the door for the virus.

Best, Joe


  
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