Jun 14, 2002
This is a hypothetical, if you develop resistance to viread does it wipe the rest of the nukes if you didn't have any resistance to them(except 3tc)I haven't seen anything published and I currently take viread(not very long)but I really want to pursue an interuption(thank you Dr. Boyle for your earlier input!!!)I guess the reason I'm asking is because when I inevitably have to restart a reg I think I would go with the viread again.I know I was undetectable when I exchanged videx for it.I'm just so tired of the unresolved side effects,I'm supposed to be living life to the fullest,but that once true reality is just a distant memory.
Response from Dr. Boyle
The studies looking at Viread (tenofovir) resistance show that the primary mutation (K65R) does not develop very often in patients on Viread (about 2%). This mutation will also cause some resistance to some other nucleosides, including Ziagen (abacavir) and Videx (didanosine). Other mutations may also affect Viread (e.g., nucleoside associated mutations, especially 210 and 41), but these do not appear to develop in patients on Viread. Finally, M184V increases the viral sensitivity to Viread; however, clinical studies presented to date have yet to show that this results in increased clinical benefit.
Get Email Notifications When This Forum Updates or Subscribe With RSS
- Is Tingling Lips A Sign Of Acute HIV Infection?
- How Do You Know If You Have Anal Cancer?
- Dry Cough After Erotic Massage Worried I Have HIV
- Herpes After Sex With Sex Worker Worried I Have HIV
- Loose Stool After Protected Anal Sex Sign Of HIV AIDS
- Pain In Penis After Protected Anal Sex Does It Mean I Have HIV
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.