|on epivir and zerit for six weeks before adding another drug
Mar 27, 2002
last year i was on combivir and rescriptor. however, by end of year billirubins were high. vl undetectable and cd4 above 400. two weeks holliday and ther started on zerit and epivir. docto told me to stay with these two drugs for six weeks. do labwork and based on results add another drug. could it be any drug resistance to epivir and zerit in six weeks before adding another one? thank you for your help. x
| Response from Dr. Boyle
Yers, it is possible to develop resistance if on two nucleoside analogues alone for 6 weeks, especially to Epivir (lamivudine) which takes only one point mutation for high-grade resistance to develop. This is not an advisable way to manage antiretroviral therapy.
Get Email Notifications When This Forum Updates or Subscribe With RSS
This forum is designed for educational purposes only, and experts are not rendering medical, mental health, legal or other professional advice or services. If you have or suspect you may have a medical, mental health, legal or other problem that requires advice, consult your own caregiver, attorney or other qualified professional.
Experts appearing on this page are independent and are solely responsible for editing and fact-checking their material. Neither TheBody.com nor any advertiser is the publisher or speaker of posted visitors' questions or the experts' material.